Financiado en parte por BT Group, Kagome Co., Ltd
Brain Training and Sulforaphane Intake Interventions Separately Improve Cognitive Performance in Healthy Older Adults, Whereas a Combination of These Interventions Does Not Have More Beneficial Effects: Evidence from a Randomized Controlled Trial
Nouchi R, Hu Q, Saito T, Kawata NYDS, Nouchi H, Kawashima R
Nutrients · 28 citas
Etiquetas de revisión
Vínculos de autores con la industriaFinanciado por la industriaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiado por la industria
- Empresa
- BT Group
- Gobierno
- Japan Society for the Promotion of Science
- Gobierno
- the Japan Society for the Promotion of Science KAKENHI
- Empresa
- Kagome Co., Ltd
- Autores
- Al menos un autor declara un vínculo económico con la industria
- Subvenciones
- Japan Society for the Promotion of Science (15H05366); Japan Society for the Promotion of Science (19H01760); Japan Society for the Promotion of Science (15H05366 (Grant-in-Aid for Young Scientists (A))); Japan Society for the Promotion of Science (16KT0002 (Grant-in-Aid for Scientific Research (B))); Japan Society for the Promotion of Science (16KT0002); Japan Society for the Promotion of Science (17H06046)
Según 4 financiadores declarados y la declaración de financiación del texto completo.
Publicación
- Publicado
- 2021-01-25 · Nutrients · vol. 13 · número 2 · pág. 352
- Editorial
- Multidisciplinary Digital Publishing Institute
- Citado
- 34 citas · más que el 96% de estudios similares · 5.6× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 45 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY
- Áreas de investigación
- Cognitive Abilities and Testing · Dementia and Cognitive Impairment Research · Cognitive Functions and Memory
- Palabras clave
- brain training, sulforaphane, cognitive function, older adults, processing speed, working memory, combined intervention, dietary supplementation, Tetris, brain age, cognitive aging
- MeSH
- brain, humans, isothiocyanates, sulfoxides, anticarcinogenic agents, double-blind method, cognition, neuropsychological tests, games, experimental, aged, female, male, executive function
6 autores
- Rui Nouchi🇯🇵 · autor de correspondenciaTohoku University
- Qingqiang Hu🇯🇵Kagome Co., Ltd. (Japan)
- Toshiki I. Saito🇯🇵Tohoku University
- Natasha Y. S. Kawata🇯🇵Tohoku University
- Haruka Nouchi🇯🇵Tohoku University
- Ryuta Kawashima🇯🇵Tohoku University
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background
Earlier studies have demonstrated that a single-domain intervention, such as a brain-training (BT) game alone and a sulforaphane (SFN) intake, positively affects cognition. This study examined whether a combined BT and SFN intake intervention has beneficial effects on cognitive function in older adults.
Methods
In a 12-week double-blinded randomized control trial, 144 older adults were randomly assigned to one of four groups: BT with SFN (BT-S), BT with placebo (BT-P), active control game (AT) with SFN (AT-S), and active control game with placebo (AT-P). We used Brain Age in BT and Tetris in AT. Participants were asked to play BT or AT for 15 min a day for 12 weeks while taking a supplement (SFN or placebo). We measured several cognitive functions before and after the intervention period.
Results
The BT (BT-S and BT-P) groups showed more improvement in processing speed than the active control groups (AT-S and AT-P). The SFN intake (BT-S and AT-S) groups recorded significant improvements in processing speed and working memory performance unlike the placebo intake groups (BT-P and AT-P). However, we did not find any evidence of the combined intervention's beneficial effects on cognition.
Discussion
We discussed a mechanism to improve cognitive functions in the BT and SFN alone interventions.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).
Confianza de la comunidad
Cargando…
¿Cuánto confías en los hallazgos de este estudio?
Comentarios
¿Algo está mal aquí?
Señala este estudio si su información, etiquetas o financiación parecen incorrectas. Un editor revisa cada señalamiento.
Información educativa sobre investigación publicada. No es consejo médico ni una recomendación para empezar o dejar nada.