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Time restricted eating as a weight loss intervention in adults with obesity

Przulj D, Ladmore D, Smith KM, Phillips-Waller A, Hajek P

PloS one · 30 citas

Cómo se estudió

Diseño
Ensayo clínico controlado (indexado por PubMed)
Estudiado en
Personas
Resultado principal
Marcadores de salud y funcionamiento

Quién lo pagó

Financiación
Financiación independiente
Organización sin fines de lucro
British Heart Foundation
Subvenciones
British Heart Foundation (PG/17/41/33038)

Según 1 financiador declarado y la declaración de financiación del texto completo.

Publicación

Publicado
2021-01-28 · PLoS One · vol. 16 · número 1 · pág. e0246186
Editorial
Public Library of Science
Citado
40 citas · más que el 94% de estudios similares · 3.6× el promedio de su campo
Impacto
Entre el 10 % más citado de su campo
Referencias
33 trabajos
Acceso
Acceso abierto (revista) · CC-BY
Áreas de investigación
Dietary Effects on Health · Enhanced Recovery After Surgery · Circadian rhythm and melatonin
Palabras clave
Medicine, Weight loss, Obesity, Weight management, Cohort, Lipid profile, Internal medicine, Cholesterol
MeSH
humans, obesity, weight loss, chronotherapy, prospective studies, pilot projects, adult, middle aged, female, male

5 autores

  • Dunja Przulj🇬🇧 · autor de correspondenciaQueen Mary University of London
  • Daniella Ladmore🇬🇧Queen Mary University of London
  • Katie Myers Smith🇬🇧Queen Mary University of London
  • Anna Phillips‐Waller🇬🇧Queen Mary University of London
  • Peter Hájek🇬🇧Queen Mary University of London

Resumen

El texto original del estudio, en el idioma en que se publicó.

Objectives

Time-restricted eating (TRE) is a weight management approach in which food is consumed only within a specific period each day. The simplicity of this approach is appealing, but its efficacy is not known. The aim of this pilot cohort study was to assess adherence to TRE and its effects on weight and lipid profile.

Methods

Fifty participants with obesity attempted to follow TRE for 12 weeks. Surveys were conducted weekly over the phone to assess treatment adherence and ratings; and at 6 and 12 weeks, participants attended the clinic to be weighed, have their blood pressure taken and provide a blood sample for lipid profile. Treatment results were compared with data from previous comparable cohorts using other weight management methods.

Results

Mean age of the participants was 50 (SD = 12.0), mean weight 97kg (SD = 17.1), mean BMI = 35 (SD = 4.0) and most were female (74%). At weeks 6 and 12, 64% and 58% of participants continued to practice TRE on at least five days/week. Using the 'last observation carried forward' imputation, mean (SD) weight loss was 2.0 (1.7) kg and 2.6 (2.6) kg at 6 and 12 weeks. Among participants who provided follow-up data, those who adhered to the intervention for at least five days/week recorded greater weight loss than those with lower adherence (week 6: 2.5 (1.7) vs 1.0 (1.3), p = 0.003; week 12: 3.5 (2.7) vs 1.3 (2.0), p = 0.001). A total of 26% of the sample lost at least 5% of their body weight at 12 weeks. The intervention had no effect on blood pressure or lipid profile.

Conclusions

TRE results were modest, but at least on par with those achieved with more complex interventions, and weight loss did not decline at 12 weeks. A formal trial of the intervention is warranted.

Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).

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