The effects of canola and olive oils consumption compared to sunflower oil, on lipid profile and hepatic steatosis in women with polycystic ovarian syndrome: a randomized controlled trial
Yahay M, Heidari Z, Allameh Z, Amani R
Lipids in health and disease · 18 citas
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
- Consumo medido con
- No se indica
Quién lo pagó
- Financiación
- Financiación independiente
Según la declaración de financiación del texto completo.
Publicación
- Publicado
- 2021-01-29 · Lipids Health Dis · vol. 20 · número 1 · pág. 7
- Editorial
- BioMed Central
- Citado
- 48 citas · más que el 98% de estudios similares · 6.7× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 107 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY
- Áreas de investigación
- Ovarian function and disorders · Diet, Metabolism, and Disease · Fatty Acid Research and Health
- Palabras clave
- polycystic ovary syndrome, canola oil, olive oil, sunflower oil, dietary intervention, lipid profile, hepatic steatosis, dyslipidemia, insulin resistance, HOMA-IR, triglycerides, cardiovascular risk
- MeSH
- humans, polycystic ovary syndrome, fatty liver, insulin resistance, lipids, fatty acids, sex hormone-binding globulin, eating, adult, female, olive oil, sunflower oil, rapeseed oil
4 autores
- Maryam Yahay🇮🇷Isfahan University of Medical Sciences
- Zahra Heidari🇮🇷Isfahan University of Medical Sciences
- Zahra Sadat Allameh🇮🇷Isfahan University of Medical Sciences
- Reza Amani🇮🇷 · autor de correspondenciaIsfahan University of Medical Sciences
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background
Polycystic Ovarian Syndrome (PCOS) is one of the most common endocrinopathies and metabolic disorders in women during their reproductive years. It is often associated with dyslipidemia and other risk factors of cardiovascular diseases (CVD). This study was aimed to evaluate dietary intervention effects with canola and olive oils compared to sunflower oil on lipid profile and fatty liver severity among women with PCOS.
Method
This study was a 10-week intervention including 72 women with PCOS. Patients were randomly assigned to three groups for receiving 25 g/day canola, olive, or sunflower oils for 10 weeks. The primary and secondary outcomes were to assess changes in lipid profile and in fatty liver severity, respectively.
Result
At the end of the study, 72 patients with a mean age of 29.31 were analysed. Canola oil consumption resulted in a significant reduction in serum levels of TG (P = 0.002) and TC/HDL (P = 0.021), LDL/HDL (P = 0.047), and TG/HDL (P = 0.001) ratios, however, there was no significant reduction in lipid profile following olive oil consumption. Canola (P < 0.001) and olive oils (P = 0.005) could significantly reduce the fatty liver grade. Moreover, HOMA-IR in both canola (P < 0.001) and olive (P = 0.004) groups was significantly decreased.
Conclusion
In total, compared to olive and sunflower oils, significant improvements in lipid profile, liver function, and HOMA-IR were observed following canola oil consumption in women with PCOS.
Trial registration
IR.MUI.
Research
REC.1397.315. Registered 30 JUNE 2019 - Retrospectively registered, https://www.irct.ir/trial/38684.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).
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