Association of ultra-processed food consumption with cardiovascular mortality in the US population: long-term results from a large prospective multicenter study
Zhong GC, Gu HT, Peng Y, Wang K, Wu YQ, Hu TY, Jing FC, Hao FB
The international journal of behavioral nutrition and physical activity · 71 citas
Etiquetas de revisión
Cuestionario de frecuencia de consumoSin ajuste declarado por estilo de vidaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Estudio de cohortes (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Eventos clínicos como enfermedad o muerte
- Consumo medido con
- Cuestionario de frecuencia de consumo
Quién lo pagó
- Financiación
- Financiación independiente
- Universidad u hospital
- Chongqing Medical University
- Gobierno
- National Cancer Institute
Según 2 financiadores declarados y la declaración de financiación del texto completo.
Publicación
- Publicado
- 2021-02-03 · Int J Behav Nutr Phys Act · vol. 18 · número 1 · pág. 21
- Editorial
- BioMed Central
- Citado
- 95 citas · más que el 99% de estudios similares · 14.4× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 61 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY
- Áreas de investigación
- Consumer Attitudes and Food Labeling · Nutrition, Genetics, and Disease · Biochemical Analysis and Sensing Techniques
- Palabras clave
- Medicine, Hazard ratio, Population, Proportional hazards model, Confidence interval, Cohort study, Prospective cohort study, Internal medicine, Demography, Environmental health
- MeSH
- humans, cardiovascular diseases, diet, prospective studies, united states, fast foods
8 autores
- Guo‐Chao Zhong🇨🇳 · autor de correspondenciaDalian Medical University; Second Affiliated Hospital of Chongqing Medical University; Chongqing Medical University
- Haitao Gu🇨🇳 · autor de correspondenciaDalian Medical University; Second Affiliated Hospital of Chongqing Medical University; Chongqing Medical University
- Yang Peng🇨🇳Chengdu Fifth People's Hospital
- Kang Wang🇨🇳The Affiliated Yongchuan Hospital of Chongqing Medical University; Chongqing Medical University
- You‐Qi‐Le Wu🇨🇳Chongqing Public Health Medical Center; Chongqing Medical University
- Tianyang Hu🇨🇳 · autor de correspondenciaDalian Medical University; Second Affiliated Hospital of Chongqing Medical University; Chongqing Medical University
- Feng-Chuang Jing🇨🇳Children's Hospital of Chongqing Medical University; Chongqing Medical University
- Fa‐Bao Hao🇨🇳Qingdao University; Qingdao Women and Children's Hospital
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background
Ultra-processed foods have now become dominant in the global food system. Whether their consumption is associated with cardiovascular mortality remains controversial. Moreover, data on ultra-processed foods and cardiovascular outcomes are scarce in the US population. We aimed to examine the association of ultra-processed food consumption with cardiovascular mortality in a US population.
Methods
A population-based cohort of 91,891 participants was identified from the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial. Dietary data were collected through a validated 137-item food frequency questionnaire. Ultra-processed foods were defined by the NOVA classification. Cox regression was used to calculate hazard ratios (HRs) and 95% confidence intervals (CIs) for cardiovascular mortality. Restricted cubic spline regression was used to test nonlinearity. Subgroup analyses were conducted to identify the potential effect modifiers.
Results
After an average follow-up of 13.5 years (1,236,049.2 person-years), 5490 cardiovascular deaths were documented, including 3985 heart disease deaths and 1126 cerebrovascular deaths. In the fully adjusted model, participants in the highest vs. the lowest quintiles of ultra-processed food consumption had higher risks of death from cardiovascular disease (HRquintile 5 vs. 1, 1.50; 95% CI, 1.36-1.64) and heart disease (HRquintile 5 vs. 1, 1.68; 95% CI, 1.50-1.87) but not cerebrovascular disease (HRquintile 5 vs. 1, 0.94; 95% CI, 0.76-1.17). A nonlinear dose-response pattern was observed for overall cardiovascular and heart disease mortality (all Pnonlinearity interaction < 0.05).
Conclusions
High consumption of ultra-processed foods is associated with increased risks of overall cardiovascular and heart disease mortality. These harmful associations may be more pronounced in women. Our findings need to be confirmed in other populations and settings.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).
Confianza de la comunidad
Cargando…
¿Cuánto confías en los hallazgos de este estudio?
Comentarios
¿Algo está mal aquí?
Señala este estudio si su información, etiquetas o financiación parecen incorrectas. Un editor revisa cada señalamiento.
Información educativa sobre investigación publicada. No es consejo médico ni una recomendación para empezar o dejar nada.