The impact of daily caffeine intake on nighttime sleep in young adult men
Weibel J, Lin YS, Landolt HP, Kistler J, Rehm S, Rentsch KM, Slawik H, Borgwardt S, Cajochen C, Reichert CF
Scientific reports · 35 citas
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- National Science Foundation
- Gobierno
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
- Organización sin fines de lucro
- Janggen-Pöhn-Stiftung
- Gobierno
- Swiss National Science Foundation
- Organización sin fines de lucro
- Nikolaus und Bertha Burckhardt-Bürgin-Stiftung
- Subvenciones
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (163058); Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (320030)
Según 5 financiadores declarados y la declaración de financiación del texto completo.
Publicación
- Publicado
- 2021-02-25 · Sci Rep · vol. 11 · número 1 · pág. 4668
- Editorial
- Nature Portfolio
- Citado
- 54 citas · más que el 97% de estudios similares · 5.9× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 53 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY
- Áreas de investigación
- Sleep and related disorders · Coffee research and impacts · Sleep and Wakefulness Research
- Palabras clave
- Caffeine, Evening, Placebo, Polysomnography, Sleep (system call), Stimulant, Morning, Crossover study, Anesthesia, Medicine, Sleep onset, Sleep Stages, Slow-wave sleep, Psychology, Electroencephalography, Internal medicine, Psychiatry, Insomnia
- MeSH
- saliva, humans, caffeine, polysomnography, cross-over studies, double-blind method, sleep, darkness, male, young adult
10 autores
- Janine Weibel🇨🇭University of Basel
- Yu-Shiuan Lin🇨🇭University of Basel
- Hans‐Peter Landolt🇨🇭University of Zurich
- Joshua Kistler🇨🇭University of Basel
- Sophia S. Rehm🇨🇭University Hospital of Basel
- KATHARINA M. RENTSCH🇨🇭University Hospital of Basel
- Helen C. Slawik🇨🇭University of Basel
- Stefan Borgwardt🇨🇭University of Basel
- Christian Cajochen🇨🇭 · autor de correspondenciaUniversity of Basel; Universitäre Psychiatrische Kliniken Basel
- Carolin Reichert🇨🇭University of Basel
Resumen
El texto original del estudio, en el idioma en que se publicó.
Acute caffeine intake can delay sleep initiation and reduce sleep intensity, particularly when consumed in the evening. However, it is not clear whether these sleep disturbances disappear when caffeine is continuously consumed during daytime, which is common for most coffee drinkers. To address this question, we investigated the sleep of twenty male young habitual caffeine consumers during a double-blind, randomized, crossover study including three 10-day conditions: caffeine (3 × 150 mg caffeine daily), withdrawal (3 × 150 mg caffeine for 8 days, then switch to placebo), and placebo (3 × placebo daily). After 9 days of continuous treatment, electroencephalographically (EEG)-derived sleep structure and intensity were recorded during a scheduled 8-h nighttime sleep episode starting 8 (caffeine condition) and 15 h (withdrawal condition) after the last caffeine intake. Upon scheduled wake-up time, subjective sleep quality and caffeine withdrawal symptoms were assessed. Unexpectedly, neither polysomnography-derived total sleep time, sleep latency, sleep architecture nor subjective sleep quality differed among placebo, caffeine, and withdrawal conditions. Nevertheless, EEG power density in the sigma frequencies (12-16 Hz) during non-rapid eye movement sleep was reduced in both caffeine and withdrawal conditions when compared to placebo. These results indicate that daily caffeine intake in the morning and afternoon hours does not strongly impair nighttime sleep structure nor subjective sleep quality in healthy good sleepers who regularly consume caffeine. The reduced EEG power density in the sigma range might represent early signs of overnight withdrawal from the continuous presence of the stimulant during the day.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).
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