Whole grain intake favorably affects blood glucose and serum triacylglycerols in overweight and obese children: A randomized controlled crossover clinical trial
Hajihashemi P, Azadbakht L, Hashemipour M, Kelishadi R, Saneei P, Esmaillzadeh A
Nutrition (Burbank, Los Angeles County, Calif.) · 6 citas
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
- Consumo medido con
- No se indica
Quién lo pagó
- Financiación
- Financiación independiente
- Universidad u hospital
- Isfahan University of Medical Sciences
Según 1 financiador declarado.
Publicación
- Publicado
- 2021-02-15 · Nutrition · vol. 87-88 · pág. 111200
- Editorial
- Elsevier BV
- Citado
- 11 citas · más que el 74% de estudios similares · 1.1× el promedio de su campo
- Referencias
- 39 trabajos
- Acceso
- De pago
- Áreas de investigación
- Food composition and properties · Nutritional Studies and Diet · Diet, Metabolism, and Disease
- Palabras clave
- whole grain intake, childhood obesity, overweight children, blood glucose, serum triglycerides, HDL cholesterol, LDL cholesterol, dietary intervention
- MeSH
- humans, obesity, blood glucose, triglycerides, child, female, overweight, whole grains
6 autores
- Parisa Hajihashemi🇮🇷Isfahan University of Medical Sciences
- Leila Azadbakht🇮🇷Isfahan University of Medical Sciences; Tehran University of Medical Sciences
- Mahin Hashemipour🇮🇷Isfahan University of Medical Sciences
- Roya Kelishadi🇮🇷Isfahan University of Medical Sciences
- Parvane Saneei🇮🇷Isfahan University of Medical Sciences
- Ahmad Esmaillzadeh🇮🇷 · autor de correspondenciaIsfahan University of Medical Sciences; Tehran University of Medical Sciences
Resumen
El texto original del estudio, en el idioma en que se publicó.
Objectives
The aim of this study was to determine the effects of whole grain consumption on the metabolic profiles of overweight or obese children.
Methods
This was a randomized crossover clinical trial with 44 overweight or obese girls. After a 2-wk run-in period, girls were randomly assigned to either intervention or control groups. Participants in the intervention group were asked to obtain 50% of their grain servings from whole grain foods each day for 6 wk. Those in the control group were asked not to consume any of these foods. A 4-wk washout period was applied following which participants were crossed over to the alternate arm. Fasting blood samples were taken before and after each phase of study.
Results
Mean (± SD) age and body mass index was 11.2 ± 1.49 y and 23.5 ± 2.5 kg/m2, respectively. Mean whole grain intake in intervention and control groups throughout the study was 26.5 and 3.7 g/d, respectively (P = 0.01). Whole grain consumption resulted in lower concentrations of plasma glucose (changes from baseline in intervention group: -0.10 versus 0.21 mmol/L in control group, P = 0.01), serum triacylglycerols (changes from baseline in intervention group: -0.18 versus 0.08 mmol/L in control group, P = 0.01) and higher concentrations of serum high-density lipoprotein cholesterol (changes from baseline in intervention group: 0.16 versus -0.14 mmol/L in control group, P = 0.05) after 6 wk of intervention. No effects of whole grain intake on serum concentrations of total- and low-density lipoprotein cholesterol or on blood pressure were found.
Conclusion
This study provided evidence supporting the beneficial effects of whole grain foods on serum concentrations of glucose, triacylglycerols and high-density lipoprotein cholesterol in overweight children.
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