The effect of low-level laser therapy on diabetic foot ulcers: A meta-analysis of randomised controlled trials
Huang J, Chen J, Xiong S, Huang J, Liu Z
International wound journal · 25 citas
Cómo se estudió
- Diseño
- Metaanálisis (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
- Universidad u hospital
- Chongqing Medical University
- Universidad u hospital
- This work was supported by Nursing Science Research Fund of Chongqing Medical University
Según 2 financiadores declarados y la declaración de financiación del texto completo.
Publicación
- Publicado
- 2021-03-09 · Int Wound J · vol. 18 · número 6 · págs. 763–776
- Editorial
- Wiley
- Citado
- 48 citas · más que el 93% de estudios similares · 3.3× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 65 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY-NC-ND
- Áreas de investigación
- Laser Applications in Dentistry and Medicine · Diabetic Foot Ulcer Assessment and Management · Wound Healing and Treatments
- Palabras clave
- low-level laser therapy, diabetic foot ulcer, wound healing, ulcer healing rate, healing time, ulcer area reduction, adjuvant therapy
- MeSH
- humans, diabetic foot, diabetes mellitus, treatment outcome, wound healing, china, randomized controlled trials as topic, low-level light therapy
5 autores
- Jing Huang🇨🇳The Affiliated Yongchuan Hospital of Chongqing Medical University
- Jiangqiong Chen🇨🇳The Affiliated Yongchuan Hospital of Chongqing Medical University
- Shuyuan Xiong🇨🇳The Affiliated Yongchuan Hospital of Chongqing Medical University
- Jingui Huang🇨🇳The Affiliated Yongchuan Hospital of Chongqing Medical University
- Zhiping Liu🇨🇳 · autor de correspondenciaThe Affiliated Yongchuan Hospital of Chongqing Medical University
Resumen
El texto original del estudio, en el idioma en que se publicó.
Our purpose was to perform a meta-analysis to evaluate the effect of Low-level laser therapy (LLLT) on diabetic foot ulcers (DFUs). The PubMed, Cochrane, Embase, Web of Science, Chinese BioMedical Literature Database (CBM), China National Knowledge Infrastructure (CNKI), VIP and Wanfang databases were searched systematically up to August 27, 2020. Studies that met the inclusion criteria were included in the analysis. A total of 13 randomised controlled trials (RCTs) and 413 patients were analysed. Compared with the control group, LLLT significantly increased the complete healing rate (risk ratio [RR] = 2.10, 95% confidence interval [CI] 1.56-2.83, P < .00001), reduced the ulcer area (standardised mean difference [SMD] = 3.52, 95% CI 1.65-5.38, P = .0002), and shortened the mean healing time (SMD = -1.40, 95% CI -1.90 to -0.91, P < .00001) of patients with DFUs. The quality of the evidence was very low according to the GRADE system. LLLT is a promising and effective adjuvant treatment to accelerate the healing of DFUs. Further evidence from larger samples and higher quality RCTs is needed to prove the effect of LLLT and to determine the most appropriate parameters for the healing of DFUs.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY-NC-ND).
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