The Effects of Time-Restricted Eating versus Standard Dietary Advice on Weight, Metabolic Health and the Consumption of Processed Food: A Pragmatic Randomised Controlled Trial in Community-Based Adults
Phillips NE, Mareschal J, Schwab N, Manoogian ENC, Borloz S, Ostinelli G, Gauthier-Jaques A, Umwali S, Gonzalez Rodriguez E, Aeberli D, Hans D, Panda S, Rodondi N, Naef F, Collet TH
Nutrients · 97 citas
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
- Organización sin fines de lucro
- Fondation Leenaards
- Organización sin fines de lucro
- Schweizerische Multiple Sklerose Gesellschaft
- Organización sin fines de lucro
- Vontobel-Stiftung
- Organización sin fines de lucro
- Schweizerischen Gesellschaft für Endokrinologie und Diabetologie
- Gobierno
- Swiss National Science Foundation
- Subvenciones
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (167826)
Según 6 financiadores declarados y la declaración de financiación del texto completo.
Publicación
- Publicado
- 2021-03-23 · Nutrients · vol. 13 · número 3 · pág. 1042
- Editorial
- Multidisciplinary Digital Publishing Institute
- Citado
- 106 citas · más que el 99% de estudios similares · 8.2× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 45 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY
- Áreas de investigación
- Dietary Effects on Health · Diet and metabolism studies · Eating Disorders and Behaviors
- Palabras clave
- Consumption (sociology), Medicine, Healthy eating, Randomized controlled trial, Environmental health, Gerontology, Food science, Physical therapy, Biology, Physical activity, Internal medicine
- MeSH
- humans, obesity, body weight, weight loss, exercise, nutrition therapy, diet therapy, diet, body composition, eating, time factors, adolescent, adult, aged, middle aged, female, male, young adult, fast foods, smartphone, metabolic syndrome
15 autores
- Nicholas Edward Phillips🇨🇭École Polytechnique Fédérale de Lausanne
- Julie Mareschal
- Nathalie Schwab🇨🇭University of Bern; University Hospital of Bern; University of Lausanne
- Emily N. C. Manoogian🇺🇸Salk Institute for Biological Studies
- Sylvie Borloz🇨🇭University of Lausanne
- Giada Ostinelli🇨🇦🇨🇭Institut universitaire de cardiologie et de pneumologie de Québec; Université Laval; University of Lausanne
- Aude Gauthier-Jaques🇨🇭University of Lausanne
- Sylvie Umwali🇨🇭University of Lausanne
- Elena González Rodríguez🇨🇭University of Lausanne
- Daniel Aeberli🇨🇭University of Bern; University Hospital of Bern
- Didier B. Hans🇨🇭University of Lausanne
- Satchidananda Panda🇺🇸Salk Institute for Biological Studies
- Nicolas Rodondi🇨🇭University of Bern; University Hospital of Bern
- Félix Naef🇨🇭École Polytechnique Fédérale de Lausanne
- Tinh‐Hai Collet🇨🇭 · autor de correspondenciaUniversity of Lausanne
Resumen
El texto original del estudio, en el idioma en que se publicó.
Weight loss is key to controlling the increasing prevalence of metabolic syndrome (MS) and its components, i.e., central obesity, hypertension, prediabetes and dyslipidaemia. The goals of our study were two-fold. First, we characterised the relationships between eating duration, unprocessed and processed food consumption and metabolic health. During 4 weeks of observation, 213 adults used a smartphone application to record food and drink consumption, which was annotated for food processing levels following the NOVA classification. Low consumption of unprocessed food and low physical activity showed significant associations with multiple MS components. Second, in a pragmatic randomised controlled trial, we compared the metabolic benefits of 12 h time-restricted eating (TRE) to standard dietary advice (SDA) in 54 adults with an eating duration > 14 h and at least one MS component. After 6 months, those randomised to TRE lost 1.6% of initial body weight (SD 2.9, p = 0.01), compared to the absence of weight loss with SDA (-1.1%, SD 3.5, p = 0.19). There was no significant difference in weight loss between TRE and SDA (between-group difference -0.88%, 95% confidence interval -3.1 to 1.3, p = 0.43). Our results show the potential of smartphone records to predict metabolic health and highlight that further research is needed to improve individual responses to TRE such as a shorter eating window or its actual clock time.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).
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