Financiado en parte por Almond Board of California
Almond Bioaccessibility in a Randomized Crossover Trial: Is a Calorie a Calorie?
Nishi SK, Kendall CWC, Bazinet RP, Hanley AJ, Comelli EM, Jenkins DJA, Sievenpiper JL
Mayo Clinic proceedings · 9 citas
Etiquetas de revisión
Financiado por la industriaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
- Consumo medido con
- Diarios o recordatorios de alimentación
Quién lo pagó
- Financiación
- Financiado por la industria
- Grupo de la industria
- Almond Board of California
- Organización sin fines de lucro
- Physicians' Services Incorporated Foundation
- Universidad u hospital
- University of Toronto
- Gobierno
- Canadian Institutes of Health Research
- Universidad u hospital
- Banting and Best Diabetes Centre, University of Toronto
- Gobierno
- CIHR
- Organización sin fines de lucro
- Physicians' Services Inc Foundation
- Universidad u hospital
- University of Toronto Banting and Best Diabetes Centre
Según 8 financiadores declarados.
Publicación
- Publicado
- 2021-04-13 · Mayo Clin Proc · vol. 96 · número 9 · págs. 2386–2397
- Editorial
- Elsevier BV
- Citado
- 11 citas · más que el 76% de estudios similares · 1.2× el promedio de su campo
- Referencias
- 36 trabajos
- Acceso
- Acceso abierto (revista híbrida) · CC-BY
- Áreas de investigación
- Nuts composition and effects · Food composition and properties · Fatty Acid Research and Health
- Palabras clave
- almond, bioaccessibility, hyperlipidemia, fat excretion, dietary fat, Atwater factors, dietary supplements, muffins, serum lipids, fatty acids, postmenopausal women
- MeSH
- humans, lipids, cross-over studies, energy intake, postmenopause, aged, middle aged, female, male, hyperlipidemias, prunus dulcis, nutrients
7 autores
- Stephanie K. Nishi🇨🇦St. Michael's Hospital; University of Toronto
- Cyril W.C. Kendall🇨🇦St. Michael's Hospital; University of Toronto; University of Saskatchewan
- Richard Paul Bazinet🇨🇦University of Toronto
- Anthony J. Hanley🇨🇦University of Toronto
- Elena M. Comelli🇨🇦University of Toronto
- David J.A. Jenkins🇨🇦St. Michael's Hospital; University of Toronto
- John L. Sievenpiper🇨🇦 · autor de correspondenciaSt. Michael's Hospital; University of Toronto
Resumen
El texto original del estudio, en el idioma en que se publicó.
Objective
To investigate the energy and macronutrient bioaccessibility of almonds in individuals with hyperlipidemia.
Methods
In a previously reported randomized crossover trial, men and postmenopausal women with hyperlipidemia incorporated 3 isoenergetic supplements into a National Cholesterol Education Program Step 2 diet for 1 month each between September 20, 2000, and June 27, 2001. Supplements provided consisted of full-dose almonds (73±5 g/d), half-dose almonds (38±3 g/d) plus half-dose muffins, and full-dose muffins (control). Energy and macronutrients, including individual fatty acids, were measured in the dietary supplements and fecal samples using gas chromatography and Association of Official Analytical Chemists methods. Serum was measured for lipids and fatty acids. Bioaccessibility of energy and macronutrients from almond consumption was assessed from dietary intake (7-day food records) and fecal output.
Results
Almond-related energy bioaccessibility was 78.5%±3.1%, with an average energy loss of 21.2%±3.1% (40.6 kcal/d in the full-dose almond phase). Bioaccessibility of energy and fat from the diet as a whole was significantly less with almond consumption (in both half- and full-dose phases) compared with the control. Bioaccessibility of fat was significantly different between treatment phases (P<.001) and on average lower by 5.1% and 6.3% in the half- and full-dose almond phases, respectively, compared with the control phase. Energy bioaccessibility was significantly different between the treatment phases (P=.02), decreasing by approximately 2% with the inclusion of the full dose of almonds compared with the control.
Conclusion
Energy content of almonds may not be as bioaccessible in individuals with hyperlipidemia as predicted by Atwater factors, as suggested by the increased fat excretion with almond intake compared with the control.
Trial registration
ClinicalTrials.gov identifier: NCT00507520.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).
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