Psychotherapy with Music Intervention Improves Anxiety, Depression and the Redox Status in Breast Cancer Patients Undergoing Radiotherapy: A Randomized Controlled Clinical Trial
Zeppegno P, Krengli M, Ferrante D, Bagnati M, Burgio V, Farruggio S, Rolla R, Gramaglia C, Grossini E
Cancers · 21 citas
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (clasificado por nuestro filtro de IA)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
Según la declaración de financiación del texto completo.
Publicación
- Publicado
- 2021-04-07 · Cancers (Basel) · vol. 13 · número 8 · pág. 1752
- Editorial
- Multidisciplinary Digital Publishing Institute
- Citado
- 43 citas · más que el 95% de estudios similares · 5.0× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 40 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY
- Áreas de investigación
- Music Therapy and Health · Cancer survivorship and care · Cancer-related cognitive impairment studies
- Palabras clave
- TBARS, Medicine, Breast cancer, Anxiety, Randomized controlled trial, Depression (economics), Internal medicine, Quality of life (healthcare), Radiation therapy, Cancer, Oncology, Oxidative stress, Psychiatry, Lipid peroxidation
9 autores
- Patrizia Zeppegno🇮🇹Università degli Studi del Piemonte Orientale “Amedeo Avogadro”
- Marco Krengli🇮🇹 · autor de correspondenciaUniversità degli Studi del Piemonte Orientale “Amedeo Avogadro”
- Daniela Ferrante🇮🇹Università degli Studi del Piemonte Orientale “Amedeo Avogadro”; Piedmont Reference Center for Epidemiology and Cancer Prevention
- Marco Bagnati🇮🇹Università degli Studi del Piemonte Orientale “Amedeo Avogadro”
- Vincenzo Burgio🇮🇹Università degli Studi del Piemonte Orientale “Amedeo Avogadro”
- Serena Farruggio🇮🇹Università degli Studi del Piemonte Orientale “Amedeo Avogadro”
- Roberta Rolla🇮🇹Università degli Studi del Piemonte Orientale “Amedeo Avogadro”
- Carla Maria Gramaglia🇮🇹Università degli Studi del Piemonte Orientale “Amedeo Avogadro”
- Elena Grossini🇮🇹Università degli Studi del Piemonte Orientale “Amedeo Avogadro”
Resumen
El texto original del estudio, en el idioma en que se publicó.
The aim of this study was to assess the effects of psychotherapy with music intervention (PMI) on anxiety, depression, redox status, and inflammation in breast cancer patients undergoing radiotherapy (RT). This monocentric randomized clinical trial recruited 60 patients who had a breast cancer operation and were undergoing postoperative RT. Eligible patients were randomized (1:1) in two groups: the control group (CG) received treatment as usual (n = 30), i.e., RT alone; the intervention group (PMI) received RT and psychotherapy with music intervention (n = 30), which was delivered in a group setting. Five patients were excluded after randomization. Assessments were performed at baseline (T0), at the end of RT (T1), and three months after the end of RT (T2). The main objectives of the study were the assessment of anxiety/depression, plasma glutathione (GSH), and thiobarbituric acid reactive substances (TBARS) in the two arms of the study. Our findings revealed a positive effect of PMI on anxiety, depression, resilience, and quality of life. Furthermore, a positive effect of PMI on redox status was found for the first time. Thus, in the PMI group, we found a significant increase of GSH (mean change 2.2 95%, CI 0.7 to 3.7) and a significant reduction of TBARS (mean change -1.1 95%, CI -1.8 to -0.3) at T2 vs. T0.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).
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