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Revisión sistemática2021Acceso abierto

Efficacy of Increased Salt and Water Intake on Pediatric Vasovagal Syncope: A Meta-Analysis Based on Global Published Data

Wang Y, Wang Y, Li X, Du J, Zhang H, Jin H, Liao Y

Frontiers in pediatrics · 12 citas

Cómo se estudió

Diseño
Revisión sistemática (indexado por PubMed)
Estudiado en
Personas
Resultado principal
Marcadores de salud y funcionamiento

Quién lo pagó

Financiación
Financiación independiente
Universidad u hospital
Peking University
Gobierno
Fundamental Research Funds for the Central Universities
Subvenciones
Fundamental Research Funds for the Central Universities (BMU2019LCKXJ001); Peking University (BMU2019LCKXJ001)

Según 2 financiadores declarados y la declaración de financiación del texto completo.

Publicación

Publicado
2021-05-13 · Front Pediatr · vol. 9 · pág. 663016
Editorial
Frontiers Media
Citado
17 citas · más que el 69% de estudios similares · 1.0× el promedio de su campo
Referencias
26 trabajos
Acceso
Acceso abierto (revista) · CC-BY
Áreas de investigación
Cardiovascular Syncope and Autonomic Disorders · Vestibular and auditory disorders · Electrolyte and hormonal disorders
Palabras clave
salt intake, water intake, head-up tilt, syncope recurrence, presyncope, non-pharmacological treatment, children

7 autores

  • Yaru Wang🇨🇳Peking University First Hospital
  • Yuanyuan Wang🇨🇳Peking University First Hospital
  • Xueying Li🇨🇳Peking University First Hospital
  • Junbao Du🇨🇳Ministry of Education of the People's Republic of China; Peking University First Hospital
  • Hao Zhang🇨🇳 · autor de correspondenciaShanghai Jiao Tong University; Shanghai Children's Medical Center
  • Hongfang Jin🇨🇳 · autor de correspondenciaPeking University First Hospital
  • Ying Liao🇨🇳 · autor de correspondenciaPeking University First Hospital

Resumen

El texto original del estudio, en el idioma en que se publicó.

Objective: This study was designed to assess the efficacy of increased salt and water intake in the treatment of pediatric vasovagal syncope (VVS) based on a meta-analysis of global data. Methods: Following the established inclusion criteria, seven databases, Cochrane Library, EMBASE, PubMed, Web of Science, VIP, Wanfang, and China National Knowledge Infrastructure (CNKI), were searched using specific terms. The Cochrane Bias risk assessment tool was used as a quality assessment tool of the included studies, and publication bias was assessed by funnel plots. Review Manager 5.4 software was used to analyze the efficacy of the included studies, taking the negative changing rate of the head-up tilt test (HUTT) and recurrence rate of syncope or presyncope as therapeutic efficacy evaluations. Results: In total, 5 randomized controlled trials (RCTs) were finally obtained, using the negative changing rate of the HUTT as an efficacy evaluation, while in 4 of the studies, the recurrence rate of syncope or presyncope was also evaluated. A total of 233 children with VVS were included in the salt and water intervention group. The cases in the control group were treated with non-medicinal conventional therapy. The results revealed that the negative changing rate of the HUTT in the intervention group (144/233, 61.8%) was higher than that in the control group (48/179, 26.8%), and the difference was significant (P P = 0.002). Conclusion: The current findings suggest that increased salt and water intake may increase the negative changing rates of the HUTT and reduce syncope or presyncope recurrence rates in pediatric patients with VVS.

Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).

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