Almond protects the liver in coronary artery disease: A randomized controlled clinical trial
Jamshed H, Arslan J, Sultan FT, Siddiqi HS, Qasim M, Hassan Gilani AU
JPMA. The Journal of the Pakistan Medical Association · 1 cita
Etiquetas de revisión
Alimentación controladaFinanciación no declaradaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
- Consumo medido con
- Comida provista por los investigadores
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2020-11-26 · J Pak Med Assoc · vol. 71 · número 3 · págs. 1–15
- Editorial
- Pakistan Medical Association
- Citado
- 3 citas · más que el 63% de estudios similares · 0.4× el promedio de su campo
- Referencias
- 0 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY
- Áreas de investigación
- Nuts composition and effects · Nutritional Studies and Diet · Liver Disease Diagnosis and Treatment
- Palabras clave
- almond, coronary artery disease, liver enzymes, aspartate aminotransferase, alanine aminotransferase, gamma-glutamyl transferase, hepatoprotection, dietary intervention, nut consumption
- MeSH
- liver, humans, alanine transaminase, aspartate aminotransferases, united states, coronary artery disease, prunus dulcis
7 autores
- Humaira Jamshed🇺🇸🇵🇰University of Alabama at Birmingham; Habib University
- Jamshed Arslan🇺🇸University of Alabama at Birmingham
- Fateh Ali Tipoo Sultan🇵🇰Aga Khan University
- Hasan Salman Siddiqi🇵🇰Aga Khan University
- Muhammad Qasim🇵🇰Aga Khan University; University of Karachi; Institute of Sustainable Halophyte Utilization
- Anwarul Hassan Gilani🇵🇰Aga Khan University; University of Haripur
- Admin Admin
Resumen
El texto original del estudio, en el idioma en que se publicó.
Objective
To compare the effect of Pakistani and American almonds on serum concentration of liver enzymes in coronary artery disease patients.
Methods
The randomised controlled trial was conducted at the Cardiology Clinics of Aga Khan University Hospital, Karachi, from February to July, 2012, and comprised patients who were randomised into intervention PA and AA groups and the control NI groups. Subjects in the intervention groups were provided Pakistani and American varieties of almonds 10g/day respectively with instructions to soak them overnight, remove the skin and eat them before breakfast for 12 weeks. The control group underwent no intervention. Serum concentrations of aspartate transaminase, Alanine transaminase and gamma-glutamyl transferase were analysed and compared.
Results
Of the 150 subjects, 110(73.3%) completed the study. Of them, there were 38(34.5%) in PA group, 41(37.3%) in AA, and 31(28.2%) in the NI group. Dietary almonds significantly reduced serum concentrations of aspartate transaminase, alanine transaminase and gamma-glutamyl transferase in the two intervention groups compared to the controls group (p<0.05) at 12-week follow-up.
Conclusions
A low dose of almonds was found to be an effective strategy to protect the liver.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
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