Dietary intakes of green leafy vegetables and incidence of cardiovascular diseases
Ojagbemi A, Okekunle AP, Olowoyo P, Akpa OM, Akinyemi R, Ovbiagele B, Owolabi M
Cardiovascular journal of Africa · 10 citas
Cómo se estudió
- Diseño
- Metaanálisis (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Eventos clínicos como enfermedad o muerte
- Consumo medido con
- No se indica
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- National Heart, Lung, and Blood Institute
- Gobierno
- National Human Genome Research Institute
- Gobierno
- National Institute of Neurological Disorders and Stroke
- Gobierno
- NINDS NIH HHS
- Gobierno
- NHGRI NIH HHS
- Gobierno
- NHLBI NIH HHS
- Subvenciones
- National Heart, Lung, and Blood Institute (R01HL152188); National Institute of Neurological Disorders and Stroke (R01 NS115944); National Human Genome Research Institute (U54 HG007479); National Institute of Neurological Disorders and Stroke (R01 NS107900); National Human Genome Research Institute (U24 HG009780)
Según 6 financiadores declarados.
Publicación
- Publicado
- 2021-08-31 · Cardiovasc J Afr · vol. 32 · número 4 · págs. 43–51
- Editorial
- Clinics Cardive Publishing
- Citado
- 27 citas · más que el 92% de estudios similares · 3.3× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 61 trabajos
- Acceso
- Acceso abierto (copia en repositorio)
- Áreas de investigación
- Seed and Plant Biochemistry · Antioxidant Activity and Oxidative Stress · Nutritional Studies and Diet
- Palabras clave
- Medicine, Incidence (geometry), Relative risk, Meta-analysis, Confidence interval, Cochrane Library, Cohort study, Disease, Environmental health, Internal medicine
- MeSH
- humans, vegetables, cardiovascular diseases, incidence, primary prevention, eating
7 autores
- Akin Ojagbemi🇳🇬University of Ibadan
- Akinkunmi Paul Okekunle🇳🇬University of Ibadan; University College Hospital, Ibadan
- Paul Olowoyo🇳🇬Afe Babalola University
- Onoja Matthew Akpa🇳🇬University of Ibadan
- Rufus Akinyemi🇳🇬University of Ibadan
- Bruce Ovbiagele🇺🇸University of California, San Francisco
- Mayowa Ojo Owolabi🇳🇬University College Hospital, Ibadan
Resumen
El texto original del estudio, en el idioma en que se publicó.
Aim
Low- and middle-income countries (LMICs) are currently experiencing increasing cardiovascular disease (CVD) rates. Green leafy vegetables (GLV), which are abundant in these countries, are known to be particularly rich in cardioprotective nutrients. This study sought to determine the specific effect of GLV intake on the incidence of CVD.
Methods
Previously published cohort studies on GLV intake and incidence of CVD were retrieved through a systematic search of Google Scholar, EMBASE, MEDLINE, HINARI and Cochrane Library. A methodological evaluation of studies was carried out using the network of Ottawa scale, and a fixed-effect meta-analysis was applied to estimate pooled relative risk (RR) and 95% confidence interval (CI). Heterogeneity was determined using the I2 statistic. Sensitivity analysis was done using the leave-one-study-out technique. All statistical analysis was carried out at p < 0.05 using RevMan 5.4.
Results
The pooled RR (95% CI) of incident CVD events from 17 studies was 0.93 (0.92-0.95). Specifically, GLV intake was inversely related with incident cerebral infarction (RR: 0.92; 95% CI: 0.88-0.96), heart disease (RR: 0.93; 95% CI: 0.87-0.99) and other CVD events (RR: 0.95; 95% CI: 0.93-0.98).
Conclusions
GLV intake was associated with a lower incidence of CVD, and may be a promising primary-prevention strategy against CVD events. The findings are especially important in LMICs where the burden of CVD remains high.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
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