Effect of photobiomodulation on post-operative symptoms in teeth with asymptomatic apical periodontitis treated with foraminal enlargement: A randomized clinical trial
Guimarães LDS, da Silva EAB, Hespanhol FG, Fontes KBFDC, Antunes LAA, Antunes LS
International endodontic journal · 20 citas
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- CNPQ - Conselho Nacional de Desenvolvimento Científico e Tecnológico
- Gobierno
- FAPERJ - Fundação de Amparo à Pesquisa do Estado do Rio de Janeiro
Según 2 financiadores declarados.
Publicación
- Publicado
- 2021-06-26 · Int Endod J · vol. 54 · número 10 · págs. 1708–1719
- Editorial
- Wiley
- Citado
- 26 citas · más que el 94% de estudios similares · 4.2× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 59 trabajos
- Acceso
- De pago
- Áreas de investigación
- Endodontics and Root Canal Treatments · Laser Applications in Dentistry and Medicine · Photodynamic Therapy Research Studies
- Palabras clave
- low-level laser therapy, apical periodontitis, endodontic treatment, postoperative pain, facial swelling, analgesic use, antimicrobial photodynamic therapy, single-rooted teeth, single-visit endodontic treatment, adjunctive therapy, gender differences in pain perception
- MeSH
- humans, periapical periodontitis, prospective studies, root canal therapy, root canal preparation, female, male, postoperative pain
8 autores
- Ludmila Silva Guimarães🇧🇷Universidade Federal Fluminense
- Erlange Andrade Borges Silva🇧🇷Universidade Federal Fluminense
- Fernanda Garcias Hespanhol🇧🇷Universidade Federal Fluminense
- KARLA BIANCA FERNANDES DA COSTA FONTES🇧🇷Universidade Federal Fluminense
- Lívia Azeredo Alves Antunes🇧🇷 · autor de correspondenciaUniversidade Federal Fluminense
- Livia Azeredo Alves Antunes🇧🇷Universidade Federal Fluminense
- Leonardo Santos Antunes🇧🇷Universidade Federal Fluminense
- Leonardo Santos Antunes🇧🇷 · autor de correspondenciaUniversidade Federal Fluminense
Resumen
El texto original del estudio, en el idioma en que se publicó.
Aim
To assess the efficacy of photobiomodulation in reducing post-operative symptoms and use of analgesics in teeth with asymptomatic apical periodontitis treated with foraminal enlargement in a single visit.
Methodology
This prospective double-blind, controlled, superiority, randomized clinical trial enrolled 70 patients requiring root canal treatment of one single-rooted tooth with asymptomatic apical periodontitis. The participants were randomized into one of the following two groups: 35 patients in the control group (C.G) - root canal treatment with foraminal enlargement, without any additional treatment and 35 patients in the photobiomodulation group (PBM.G) - root canal treatment with foraminal enlargement associated with photobiomodulation (antimicrobial photodynamic therapy and low-level laser therapy). The outcome variables were post-operative pain, tenderness, oedema and the use of analgesics. Pain intensity was measured using a visual analogue scale (recorded every day for 7 days, then the 14th and 30th days after root canal treatment). Facial oedema was assessed subjectively by two independent evaluators using photographs taken by one of the researchers at 48 h, 72 h and 7 days after the procedures. Data were tabulated and analysed using the Mann-Whitney U, Chi-Square, Fisher`s Exact, Student T and Ordinal Logistic Regression by Generalized Estimating Equations tests in SPSS software.
Results
There were no significant differences in post-operative pain and tenderness between the groups at any observation period (p > .05). Photobiomodulation (beta = -0.77 / p = .01), time (beta = -0.23 / p .05).
Conclusions
Photobiomodulation had no significant effect on post-operative pain, tenderness, oedema and the use of analgesics after root canal treatment with foraminal enlargement, in single-rooted teeth treated in a single visit. Register of Clinical Trials: NCT03704857. Research Ethics Committee: no 2.353.996 / CAAE 74185417.9.0000.5626.
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