Effect of oral magnesium supplementation for relieving leg cramps during pregnancy: A meta-analysis of randomized controlled trials
Liu J, Song G, Zhao G, Meng T
Taiwanese journal of obstetrics & gynecology · 8 citas
Cómo se estudió
- Diseño
- Metaanálisis (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- National Natural Science Foundation of China
- Subvenciones
- National Natural Science Foundation of China (81871173)
Según 1 financiador declarado.
Publicación
- Publicado
- 2021-07-01 · Taiwan J Obstet Gynecol · vol. 60 · número 4 · págs. 609–614
- Editorial
- Elsevier BV
- Citado
- 20 citas · más que el 60% de estudios similares · 0.6× el promedio de su campo
- Referencias
- 27 trabajos
- Acceso
- Acceso abierto (publicación gratuita) · CC-BY-NC-ND
- Áreas de investigación
- Pregnancy-related medical research · Electrolyte and hormonal disorders · Restless Legs Syndrome Research
- Palabras clave
- Medicine, Randomized controlled trial, Pregnancy, Odds ratio, Muscle cramp, Confidence interval, Childbirth, Calf muscle, Physical therapy, Anesthesia, Surgery, Internal medicine
- MeSH
- leg, humans, muscle cramp, pregnancy complications, magnesium, treatment outcome, administration, oral, pregnancy, dietary supplements, female, randomized controlled trials as topic
4 autores
- Jing Liu🇨🇳First Hospital of China Medical University; China Medical University
- Guang Song🇨🇳China Medical University
- Ge Zhao🇨🇳First Hospital of China Medical University; China Medical University
- Tao Meng🇨🇳 · autor de correspondenciaFirst Hospital of China Medical University; China Medical University
Resumen
El texto original del estudio, en el idioma en que se publicó.
Leg cramps are one of the common symptoms during pregnancy. About 30%-50% of pregnant women experience leg cramps twice a week. Leg cramps may cause severe pain and sleep disturbance, hinder performance of daily activities and may lengthen the duration of pregnancy and the type of childbirth. Several randomized controlled trial (RCT) studies focused on the effects of the magnesium supplement for relieving leg cramps. However, the results were inconsistent. Five databases were searched from their inception to July 2, 2020. We summarized the weighted mean difference (WMD) with 95% CIs for "the frequency of leg cramps after treatment", and summarized the odds ratio (OR) with 95% confidence intervals (CIs) for "recovery from leg cramps" and "side effects". Four RCTs with a total of 332 pregnant women were identified. The frequency of leg cramps after treatment was not decreased in the treatment group compared to the control group (WMD = -0.47, 95% CI: -1.14-0.20, P = 0.167). Magnesium supplementation cannot improve the recovery from leg cramps compared to the control group (OR = 0.47, 95% CI: 0.14-1.52, P = 0.207). Magnesium supplementation had no significant side effects in the treatment group compared to the control group (OR = 1.82, 95% CI: 0.90-3.69, P = 0.094). Oral magnesium supplementation is not effective in the treatment of leg cramps during pregnancy. PROSPERO: CRD42020196572.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY-NC-ND).
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