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Metaanálisis2022

Comparative effectiveness of low-level laser therapy with different wavelengths and transcutaneous electric nerve stimulation in the treatment of pain caused by temporomandibular disorders: A systematic review and network meta-analysis

Ren H, Liu J, Liu Y, Yu C, Bao G, Kang H

Journal of oral rehabilitation · 24 citas

Cómo se estudió

Diseño
Metaanálisis (indexado por PubMed)
Estudiado en
Personas
Resultado principal
Marcadores de salud y funcionamiento

Quién lo pagó

Financiación
Financiación independiente
Gobierno
National Natural Science Foundation of China
Subvenciones
National Natural Science Foundation of China (81660189)

Según 1 financiador declarado.

Publicación

Publicado
2021-07-21 · J Oral Rehabil · vol. 49 · número 2 · págs. 138–149
Editorial
Wiley
Citado
44 citas · más que el 88% de estudios similares · 1.8× el promedio de su campo
Referencias
59 trabajos
Acceso
De pago
Áreas de investigación
Temporomandibular Joint Disorders · Laser Applications in Dentistry and Medicine · Pain Management and Treatment
Palabras clave
low-level laser therapy, temporomandibular disorders, orofacial pain, laser wavelength, analgesia, non-pharmacological pain management
MeSH
humans, temporomandibular joint disorders, pain, transcutaneous electric nerve stimulation, low-level light therapy

6 autores

  • Hui Ren🇨🇳Lanzhou University
  • Jingying Liu🇨🇳Lanzhou University
  • Yang Liu🇨🇳Lanzhou University
  • Caiyun Yu🇨🇳Lanzhou University
  • Guangjie Bao🇨🇳Northwest Minzu University
  • Hong Kang🇨🇳Lanzhou University

Resumen

El texto original del estudio, en el idioma en que se publicó.

Objective

To assess the efficacy of low-level laser therapy (LLLT) with different wavelengths and transcutaneous electric nerve stimulation (TENS) and explore the optimal wavelength range of laser application in the treatment of pain caused by temporomandibular disorders (TMD).

Methods

An electronic search on PubMed, Cochrane Library, Embase, Scopus and Web of Science was undertaken to identify the randomised clinical trials (RCTs) published from database inception to 16 April 2021, aiming to compare the effects of LLLT with different wavelengths (632.8-672 nm, 780-904 nm, and 910-1100 nm) or TENS or placebo group on TMD patients pain reduction. In addition, manual search of the studies was performed. The reviewers assessed the risk of bias of individual studies with the Cochrane risk of bias tool and excluded the RCTs with a high risk of bias in any field. Meanwhile, the reviewers, after performing the network meta-analysis, assessed the quality of evidence, which contributed to network estimate via the GRADE framework.

Results

Twenty-seven RCTs with 969 patients with TMD were included. In the meta-analysis, all treatment groups showed an overall improvement in pain scores, when compared with the placebo group. LLLT with wavelength ranging from 910 nm to 1100 nm produced more pain relief in the visual analogue scale (VAS) immediately after treatment [mean difference (MD) = 4.68, 95% confidence interval (CI):(3.08,6.28)]. After one-month follow-up, LLLT with wavelength ranging from 910 nm to 1100 nm also showed superior pain-relieving effects [MD = 3.61, 95% CI: (-1.77, 8.99)]. However, no significant difference was observed. Based on the SUCRA ranking, L3 ranked first immediately after treatment and 1 month later.

Conclusion

The results of the meta-analysis showed the LLLT had better short-term efficacy than TENS in the treatment of pain caused by TMD. Better results can be achieved with higher wavelengths. Therefore, we recommended to treat TMD using LLLT with wavelength ranging from 910 nm to 1100 nm.

Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.

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