Effect of Intermittent Fasting on Non-Alcoholic Fatty Liver Disease: Systematic Review and Meta-Analysis
Yin C, Li Z, Xiang Y, Peng H, Yang P, Yuan S, Zhang X, Wu Y, Huang M, Li J
Frontiers in nutrition · 53 citas
Cómo se estudió
- Diseño
- Revisión sistemática (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- National Natural Science Foundation of China
- Gobierno
- Natural Science Foundation of Hubei Province
- Subvenciones
- Natural Science Foundation of Hubei Province (2060302); National Natural Science Foundation of China (2060302)
Según 2 financiadores declarados y la declaración de financiación del texto completo.
Publicación
- Publicado
- 2021-07-12 · Front Nutr · vol. 8 · pág. 709683
- Editorial
- Frontiers Media
- Citado
- 74 citas · más que el 92% de estudios similares · 2.5× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 34 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY
- Áreas de investigación
- Dietary Effects on Health · Liver Disease Diagnosis and Treatment · Diet, Metabolism, and Disease
- Palabras clave
- Medicine, Fatty liver, Internal medicine, Cochrane Library, Meta-analysis, Transaminase, Gastroenterology, Alanine transaminase, Weight loss, Body mass index, Intermittent fasting, Aspartate transaminase, Steatosis, Endocrinology, Disease, Obesity, Alkaline phosphatase, Enzyme, Biochemistry, Chemistry
10 autores
- Cong Yin🇨🇳Hubei University of Chinese Medicine
- Zihan Li🇨🇳Hubei University of Chinese Medicine
- Yulin Xiang🇨🇳Hubei University of Chinese Medicine
- Hongbing Peng🇨🇳Hubei University of Chinese Medicine
- Ping Chang Yang🇨🇳Hubei University of Chinese Medicine
- Shijun Yuan🇨🇳Hubei University of Chinese Medicine
- Xueyan Zhang🇨🇳Hubei University of Chinese Medicine
- You Wu🇨🇳Hubei University of Chinese Medicine
- Min Huang🇨🇳 · autor de correspondenciaHubei University of Chinese Medicine
- Juan Li🇨🇳 · autor de correspondenciaHubei University of Chinese Medicine
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background: Weight loss by lifestyle modification is the cornerstone therapy of non-alcoholic fatty liver disease (NAFLD). Intermittent fasting has shown favorable effects on body weight (BW) and relevant indicators of NAFLD in several reports. Objective: To estimate the effects of intermittent fasting on adults with NAFLD. Materials and methods: Literature searches were conducted on PubMed, EMBASE, Web of Science, Cochrane Library, and ClinicalTrials.gov from inception to May 10, 2021. Results: A total of six studies involving 417 patients with NAFLD were included. In the meta-analysis, there were significant differences in BW, body mass index (BMI), alanine aminotransferase (ALT), and aspartate transaminase (AST) between the control and fasting group. Up to now, there is no significant difference in triglycerides (TG), total cholesterol (TC), and other metabolic parameters between the two groups. Conclusions: Intermittent fasting is beneficial for weight management and liver enzyme improvement, but long-term feasibility and safety of intermittent fasting should be conducted in further studies.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).
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