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Effectiveness of Receptive Music Therapy with Imbedded 10 Hz Binaural Beats Compared with Standard Care for Patients with Major Depressive Disorder: A Randomized Controlled Trial

Daengruan P, Chairat R, Jenraumjit R, Chinwong D, Oon-Arom A, Klaphajone J, Arunmanakul P

Complementary therapies in medicine · 13 citas

Cómo se estudió

Diseño
Ensayo controlado aleatorizado (indexado por PubMed)
Estudiado en
Personas
Resultado principal
Marcadores de salud y funcionamiento

Quién lo pagó

Financiación
Financiación independiente
Universidad u hospital
Chiang Mai University

Según 1 financiador declarado.

Publicación

Publicado
2021-08-08 · Complement Ther Med · vol. 61 · pág. 102765
Editorial
Elsevier BV
Citado
22 citas · más que el 91% de estudios similares · 3.1× el promedio de su campo
Impacto
Entre el 10 % más citado de su campo
Referencias
27 trabajos
Acceso
Acceso abierto (revista) · CC-BY-NC-ND
Áreas de investigación
Music Therapy and Health · Treatment of Major Depression · Psychotherapy Techniques and Applications
Palabras clave
music therapy, binaural beats, major depressive disorder, depression, quality of life, medication adherence, PHQ-9, adjunctive therapy
MeSH
humans, treatment outcome, music therapy, depression, quality of life, music, adult, young adult, major depressive disorder

7 autores

  • Panitan Daengruan🇹🇭Chiang Mai University
  • Rattapong Chairat🇹🇭Chiang Mai University
  • Rewadee Jenraumjit🇹🇭Chiang Mai University
  • Dujrudee Chinwong🇹🇭Chiang Mai University
  • Awirut Oon‐arom🇹🇭Chiang Mai University
  • Jakkrit Klaphajone🇹🇭 · autor de correspondenciaChiang Mai University
  • Poukwan Arunmanakul🇹🇭 · autor de correspondenciaChiang Mai University

Resumen

El texto original del estudio, en el idioma en que se publicó.

Objectives

The purpose of this study was to determine the effectiveness of music therapy (MT) with imbedded 10 Hz binaural beats in combination with standard treatment in comparison to standard treatment alone in patients diagnosed with major depressive disorder (MDD).

Methods

This study was a randomized controlled trial enrolling 18 MDD adult patients aged ≥20 years old with mild to moderate levels of acute phase depression. The intervention group received MT along with standard treatment, while the control group received only standard treatment. 10-Hz binaural beats were embedded into soothing music. The participants listened to the MT via stereo headphones for 20 min at the clinic and were instructed to continue listening to the track at home at least 3 times/week. The primary outcome was depression score using patient health questionnaire depression screening (PHQ-9). The secondary outcomes were quality of life, measured by the Euro Quality of Life Five-Dimension (EQ-5D) rating, and medications adherence, measured by the medication adherence rating scale (MARS). The outcomes were measured at week 0, week 4, and week 8.

Results

At baseline, the primary outcome of PHQ-9 did not differ between the MT group and the control group (13.3 ± 4.4; 13.9 ± 3.37; p-value = 0.77). After a follow-up of 4 and 8 weeks, the PHQ-9 in the MT group was lower than the control group by 1.50 (95 % confidence interval: -4.46 to 1.46). However, this difference was not significant, with p-value = 0.32. As for the secondary outcome, there were no significant differences in terms of EQ-5D and MARS.

Conclusions

This study concluded that MDD patients who received 10-Hz binaural beat imbedded MT combined with standard treatment had experienced no significant differences compared with control group in terms of depression score, quality of life, and medication adherence. Further studies are suggested to investigate the long-term effect of MT with binaural beats.

Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY-NC-ND).

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