The associations between whole grain and refined grain intakes and serum C-reactive protein
Taskinen RE, Hantunen S, Tuomainen TP, Virtanen JK
European journal of clinical nutrition · 19 citas
Etiquetas de revisión
Solo mecanismosDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Estudio transversal (clasificado por nuestro filtro de IA)
- Estudiado en
- Personas
- Resultado principal
- Solo mecanismos
- Consumo medido con
- Diarios o recordatorios de alimentación
Quién lo pagó
- Financiación
- Financiación independiente
- Universidad u hospital
- Itä-Suomen Yliopisto
- Universidad u hospital
- Kuopion Yliopistollinen Sairaala
Según 2 financiadores declarados y la declaración de financiación del texto completo.
Publicación
- Publicado
- 2021-08-17 · Eur J Clin Nutr · vol. 76 · número 4 · págs. 544–550
- Editorial
- Springer Nature
- Citado
- 31 citas · más que el 85% de estudios similares · 1.9× el promedio de su campo
- Referencias
- 46 trabajos
- Acceso
- Acceso abierto (revista híbrida) · CC-BY
- Áreas de investigación
- Food composition and properties · Celiac Disease Research and Management · Nutritional Studies and Diet
- Palabras clave
- Whole grains, Food science, Medicine, C-reactive protein, Environmental health, Chemistry, Internal medicine
- MeSH
- humans, c-reactive protein, diet, dietary fiber, female, male, edible grain, whole grains
4 autores
- Riikka E. Taskinen🇫🇮University of Eastern Finland
- Sari Hantunen🇫🇮University of Eastern Finland
- Tomi‐Pekka Tuomainen🇫🇮University of Eastern Finland
- Jyrki K. Virtanen🇫🇮 · autor de correspondenciaUniversity of Eastern Finland
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background/objectives
Epidemiological studies suggest that whole grain intake has inverse associations with low-grade inflammation, but findings regarding refined grains are inconclusive. Our objective was to investigate whether consumption of whole or refined grains is associated with serum high sensitivity CRP (hs-CRP).
Subjects/methods
The study included 756 generally healthy men and women aged 53-73 years from the Kuopio Ischaemic Heart Disease Risk Factory Study, examined in 1999-2001. Dietary intakes were assessed using 4-day food records. ANCOVA and linear regression were used for analyses.
Results
The mean intake of whole and refined grains was 136 g/day (SD 80) and 84 g/day (SD 46), respectively. Higher whole grain intake was associated with lower hs-CRP concentration and higher refined grain intake with higher concentration after adjustment for lifestyle and dietary factors. Each 50 g/d higher whole grain intake was associated with 0.12 mg/L (95% Cl 0.02-0.21 mg/L) lower hs-CRP concentration and each 50 g/d higher refined grain intake with 0.23 mg/L (95% Cl 0.08-0.38) higher concentration. Adjustment for fibre from grains attenuated the associations especially with whole grains. There were no statistically significant interactions according to gender or BMI (P for interactions >0.065).
Conclusions
The results of this study suggest that higher intake of whole grains is associated with lower concentrations of hs-CRP and higher intake of refined grains is associated with higher concentrations. However, especially the association with whole grain intake was attenuated after adjusting for fibre intake from grains, suggesting that cereal fibre may partly explain the association.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).
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