Missing puzzle pieces of time-restricted-eating (TRE) as a long-term weight-loss strategy in overweight and obese people? A systematic review and meta-analysis of randomized controlled trials
Chen JH, Lu LW, Ge Q, Feng D, Yu J, Liu B, Zhang R, Zhang X, Ouyang C, Chen F
Critical reviews in food science and nutrition · 37 citas
Cómo se estudió
- Diseño
- Metaanálisis (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- National Natural Science Foundation of China
- Gobierno
- Shenzhen Science and Technology Program
- Gobierno
- Guangdong Province Zhujiang Talent Program
- Subvenciones
- National Natural Science Foundation of China (31601472)
Según 3 financiadores declarados.
Publicación
- Publicado
- 2021-09-23 · Crit Rev Food Sci Nutr · vol. 63 · número 15 · págs. 2331–2347
- Editorial
- Taylor & Francis
- Citado
- 46 citas · más que el 81% de estudios similares · 1.3× el promedio de su campo
- Referencias
- 63 trabajos
- Acceso
- De pago
- Áreas de investigación
- Dietary Effects on Health · Diet and metabolism studies · Circadian rhythm and melatonin
- Palabras clave
- Overweight, Meta-analysis, Weight loss, Term (time), Randomized controlled trial, Medicine, Obesity, Gerontology, Psychology, Pediatrics, Internal medicine
- MeSH
- humans, obesity, weight loss, overweight, cholesterol, ldl, randomized controlled trials as topic
10 autores
- Jie‐Hua Chen🇨🇳Shenzhen University
- Louise Weiwei Lu🇳🇿University of Auckland
- Qian Ge🇨🇳Jinan University; Southern University of Science and Technology
- Dana Feng🇨🇳Sun Yat-sen University; Sun Yat-sen Memorial Hospital
- Jianfeng Yu🇨🇳Shenzhen University
- Bin Liu🇨🇳Shenzhen University
- Ruijie Zhang🇨🇳Shenzhen University
- Xinying Zhang🇨🇳Shenzhen University
- Caiqun Ouyang🇨🇳 · autor de correspondenciaJinan University; Southern University of Science and Technology
- Feng Chen🇨🇳 · autor de correspondenciaShenzhen University
Resumen
El texto original del estudio, en el idioma en que se publicó.
The efficacy of using time restricted eating (TRE) for weight management and to mitigate metabolic disorders in overweight and obese people remains debatable. This meta-analysis quantified the impact of TRE on weight loss and metabolic health in overweight and obese people. The pooled results were subjected to a random-effects modeling using Hartung-Knapp-Sidik-Jonkman (HKSJ) method. Additionally, subgroup analysis was conducted based on study types, randomized controlled trials (RCTs) vs. non-randomized studies of interventions (NRSIs). Pooled results showed that subjects on TRE regimen (> 4 weeks) achieved a significant weight loss in comparison with unrestricted time regimen (weighted mean difference: -2.32%; 95% CI: -3.50, -1.14%; p < 0.01); however, weight loss was mainly attributed to the loss of lean mass rather than fat mass. The magnitude of weight loss was inversely correlated with daily fasting duration in RCTs. TRE significantly decreased the diastolic blood pressure and fasting insulin. An increase of low-density lipoprotein cholesterol (LDL-C) was observed in the TRE group. Favorable effect of TRE was observed on glucose metabolism but not on lipid profiles independent of weight loss. Hence TRE shall be administered with caution to overweight and obese people who have comorbidities such as dyslipidemia and sarcopenia.Supplemental data for this article is available online at https://doi.org/10.1080/10408398.2021.1974335.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
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