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Egg and Dietary Cholesterol Consumption and Mortality Among Hypertensive Patients: Results From a Population-Based Nationwide Study

Wu F, Zhuang P, Zhang Y, Zhan C, Zhang Y, Jiao J

Frontiers in nutrition · 7 citas

Etiquetas de revisión

Sin ajuste declarado por estilo de vida

Datos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.

Cómo se estudió

Diseño
Estudio de cohortes (clasificado por nuestro filtro de IA)
Estudiado en
Personas
Resultado principal
Eventos clínicos como enfermedad o muerte
Consumo medido con
Diarios o recordatorios de alimentación

Quién lo pagó

Financiación
Financiación independiente
Gobierno
National Natural Science Foundation of China
Gobierno
National Institute for Nutrition and Health
Gobierno
National Institutes of Health
Universidad u hospital
China-Japan Friendship Hospital
Gobierno
Fogarty International Center
Gobierno
National Institute of Diabetes and Digestive and Kidney Diseases
Gobierno
National Institute of Child Health and Human Development
Gobierno
Eunice Kennedy Shriver National Institute of Child Health and Human Development
Subvenciones
Eunice Kennedy Shriver National Institute of Child Health and Human Development ([P2C HD050924]); China-Japan Friendship Hospital (P2C HD050924); China-Japan Friendship Hospital (D43 TW009077); National Institute of Child Health and Human Development (P2CHD050924); Eunice Kennedy Shriver National Institute of Child Health and Human Development (R01DK104371); National Institute of Diabetes and Digestive and Kidney Diseases (D43 TW009077); Eunice Kennedy Shriver National Institute of Child Health and Human Development (HD30880); National Institute of Diabetes and Digestive and Kidney Diseases (R01 HD30880); Eunice Kennedy Shriver National Institute of Child Health and Human Development (D43 TW009077); National Institute of Child Health and Human Development (R01-HD30880); National Institute for Nutrition and Health (D43 TW009077); National Institute of Diabetes and Digestive and Kidney Diseases (R01- DK104371); National Institute for Nutrition and Health (P2C HD050924); Eunice Kennedy Shriver National Institute of Child Health and Human Development (R01 HD 30880); Fogarty International Center (R01-HD30880); Eunice Kennedy Shriver National Institute of Child Health and Human Development (HD050924); Fogarty International Center (P2C HD050924); Fogarty International Center (D43‐TW009077); National Institutes of Health (#P2C HD050924); National Institutes of Health (R01 HD30880); National Institutes of Health (HD30880); National Institutes of Health (#HD050924); National Institutes of Health (R01-DK104371); National Institutes of Health (D43-TW-009077)

Según 8 financiadores declarados y la declaración de financiación del texto completo.

Publicación

Publicado
2021-10-29 · Front Nutr · vol. 8 · pág. 739533
Editorial
Frontiers Media
Citado
9 citas · más que el 81% de estudios similares · 1.4× el promedio de su campo
Referencias
55 trabajos
Acceso
Acceso abierto (revista) · CC-BY
Áreas de investigación
Nutritional Studies and Diet · Diet and metabolism studies · Consumer Attitudes and Food Labeling
Palabras clave
Medicine, Cholesterol, Dietary Cholesterol, Hazard ratio, Proportional hazards model, Cohort study, Cohort, Population, Demography, Internal medicine, Environmental health, Confidence interval

6 autores

  • Fei Ling Wu🇨🇳Second Affiliated Hospital of Zhejiang University
  • Pan Zhuang🇨🇳Zhejiang University
  • Yiju Zhang🇨🇳Zhejiang University
  • Chuchu Zhan🇨🇳Zhejiang University
  • Yu Zhang🇨🇳Zhejiang University
  • Jingjing Jiao🇨🇳 · autor de correspondenciaSecond Affiliated Hospital of Zhejiang University

Resumen

El texto original del estudio, en el idioma en que se publicó.

Background: Hypertensive patients are sensitive to the amount of dietary cholesterol intake, especially cholesterol from the whole eggs. Whether whole egg and dietary cholesterol consumption are suitable for hypertensive patients is still controversial. Aim: The objective of the study was to examine the associations of intake of eggs as well as the dietary cholesterol with total mortality in a Chinese nationwide cohort. Methods: We utilized data from the China Health and Nutrition Survey (CHNS) from the year of 1991 to 2015. Cumulative averages of egg and cholesterol intake were calculated to represent the consumption of the long-term diet of the participants in each available round of the survey. Cox regression models were employed to estimate the effects of eggs and dietary cholesterol from the different sources on mortality among hypertensive patients. Results: A total of 8,095 participants were included in the final analysis and followed up for a mean of 11.4 years. Finally, 927 cases of death were detected. After adjustment for the multivariate factors, consuming more than seven eggs per week was related to 29% lower mortality among the hypertensive patients compared with the consumers with not more than two eggs per week [hazard ratio (HR): 0.71; 95% CI: 0.59-0.85; P P = 0.002) whereas intake of the dietary cholesterol from the non-egg sources was significantly related to the higher mortality (P Conclusion: Higher consumption of eggs and egg-sourced dietary cholesterol was associated with lower mortality among the enrolled Chinese hypertensive patients but non-egg-sourced cholesterol intake was related to higher mortality. Therefore, our findings do not support the view that hypertensive patients should avoid whole egg consumption for the purpose of restricting dietary cholesterol intake.

Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).

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