Effects of whole grain intake on glycemic traits: A systematic review and meta-analysis of randomized controlled trials
Li S, Zong A, An R, Wang H, Liu L, Liu J, Guo X, Xu Z, Wang J, Li D, Du F, Xu T
Critical reviews in food science and nutrition · 15 citas
Cómo se estudió
- Diseño
- Metaanálisis (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
- Consumo medido con
- No se indica
Quién lo pagó
- Financiación
- Financiación independiente
- Universidad u hospital
- Beijing Advanced Innovation Center for Food Nutrition and Human Health
- Universidad u hospital
- Open Project Program of China-Canada Joint Lab of Food Nutrition and Health, Beijing Technology and Business University
- Gobierno
- National Key R & D Project
- Subvenciones
- Beijing Advanced Innovation Center for Food Nutrition and Human Health (20171030)
Según 3 financiadores declarados.
Publicación
- Publicado
- 2021-11-18 · Crit Rev Food Sci Nutr · vol. 63 · número 20 · págs. 4351–4370
- Editorial
- Taylor & Francis
- Citado
- 24 citas · más que el 66% de estudios similares · 0.8× el promedio de su campo
- Referencias
- 74 trabajos
- Acceso
- Acceso abierto (copia en repositorio) · CC-BY
- Áreas de investigación
- Food composition and properties · Nutritional Studies and Diet · Diet and metabolism studies
- Palabras clave
- Meta-analysis, Glycemic, Randomized controlled trial, Whole grains, Medicine, Glycemic index, Food science, Internal medicine, Biology, Insulin
- MeSH
- humans, diabetes mellitus, type 2, insulin resistance, insulin, blood glucose, randomized controlled trials as topic, whole grains, glycated hemoglobin
12 autores
- Shixiang Li🇨🇳Shandong Academy of Agricultural Sciences; Ministry of Agriculture and Rural Affairs; Shandong Agricultural University
- Aizhen Zong🇨🇳Shandong Academy of Agricultural Sciences; Ministry of Agriculture and Rural Affairs; Shandong Agricultural University
- Ran An🇨🇳Shandong Normal University; Shandong Academy of Agricultural Sciences; Ministry of Agriculture and Rural Affairs
- Haiou Wang🇨🇳Shandong Academy of Agricultural Sciences; Ministry of Agriculture and Rural Affairs
- Lina Liu🇨🇳Shandong Academy of Agricultural Sciences; Ministry of Agriculture and Rural Affairs
- Jie Liu🇨🇳Beijing Technology and Business University
- Xiaofei Guo🇨🇳Qingdao University
- Zhixiang Xu🇨🇳Shandong Agricultural University
- Jing Wang🇨🇳Beijing Technology and Business University
- Duo Li🇨🇳Qingdao University
- Fangling Du🇨🇳 · autor de correspondenciaShandong Academy of Agricultural Sciences; Ministry of Agriculture and Rural Affairs
- Tongcheng Xu🇨🇳 · autor de correspondenciaBeijing Technology and Business University; Shandong Normal University; Shandong Academy of Agricultural Sciences; Ministry of Agriculture and Rural Affairs; Shandong Agricultural University
Resumen
El texto original del estudio, en el idioma en que se publicó.
Whole grains (WGs) may have various health benefits, including lowering blood glucose and improving insulin sensitivity. To conduct a meta-analysis of the effects of WGs compared with non-WGs on changes in fasting glucose, fasting insulin, glycated hemoglobin (HbA1c), and homeostasis model assessment of insulin resistance (HOMA-IR). A systematic literature search was performed for all published randomized controlled trials on the effects of WG intake on fasting glucose, fasting insulin, HbA1c and HOMA-IR response up to February 2021. Weighted mean differences (WMD) were calculated. Pre-specified subgroup and univariate meta-regression analyses were explored to identify the sources of heterogeneity. Sensitivity analysis and bias analysis were conducted to appraise study quality. Among 12,435 articles screened for eligibility, data were extracted from 48 articles. Meta-analysis of 4,118 participants showed that WG consumption resulted in a significant reduction in fasting glucose by -0.15 mmol/L, fasting insulin by -2.71 pmol/L, HbA1c by -0.44%, and HOMA-IR by -0.28, respectively. Compared with mixed grains, brown rice, and wheat, oats were significantly lower on marker of glycemic. Besides, multiple interventions per day consolidated effectiveness of WGs. WG consumption decreased the levels of fasting glucose, fasting insulin, HbA1c, and HOMA-IR compared with non-WG consumption.Supplemental data for this article is available online at https://doi.org/10.1080/10408398.2021.2001429 .
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
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