Effect of pecan nuts and extra-virgin olive oil on glycemic profile and nontraditional anthropometric indexes in patients with coronary artery disease: a randomized clinical trial
Dos Santos JL, Portal VL, Markoski MM, de Quadros AS, Bersch-Ferreira Â, Marcadenti A
European journal of clinical nutrition · 9 citas
Etiquetas de revisión
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Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
- Consumo medido con
- No se indica
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2021-11-22 · Eur J Clin Nutr · vol. 76 · número 6 · págs. 827–834
- Editorial
- Springer Nature
- Citado
- 13 citas · más que el 77% de estudios similares · 1.2× el promedio de su campo
- Referencias
- 55 trabajos
- Acceso
- De pago
- Áreas de investigación
- Nuts composition and effects · Nutritional Studies and Diet · Diabetes, Cardiovascular Risks, and Lipoproteins
- Palabras clave
- pecan nuts, extra virgin olive oil, coronary artery disease, glycemic profile, triglyceride-glucose index, anthropometric index, body fat distribution, diet quality, Alternative Healthy Eating Index, secondary prevention of cardiovascular disease, dysglycemia
- MeSH
- humans, carya, nuts, cardiovascular diseases, blood glucose, diet, mediterranean, coronary artery disease, olive oil
6 autores
- Júlia Lorenzon dos Santos🇧🇷Fundação Universitária de Cardiologia
- Vera Lúcia Portal🇧🇷Fundação Universitária de Cardiologia
- Melissa Medeiros Markoski🇧🇷Universidade Federal de Ciências da Saúde de Porto Alegre
- Alexandre Schaan de Quadros🇧🇷Fundação Universitária de Cardiologia
- Ângela Cristine Bersch-Ferreira🇧🇷Hospital do Coração
- Aline Marcadenti🇧🇷 · autor de correspondenciaFundação Universitária de Cardiologia; Hospital do Coração
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background/objectives
The influence of cardioprotective foods on nontraditional indexes related to dysglycemia and body fat distribution is unknown in individuals with coronary artery disease (CAD). This study aimed to evaluate the effect of a healthy diet supplemented with pecan nuts or extra-virgin olive oil on glycemic profile and adipose tissue dysfunction assessed by anthropometric indexes in patients with stable CAD.
Subjects/methods
In a randomized, pragmatic, parallel clinical trial lasting 12 weeks, 204 individuals were allocated to three interventions: a healthy diet (control group [CG], n = 67), a healthy diet plus 30 g/day of pecan nuts (pecan nut group [PNG], n = 68), or a healthy diet plus 30 mL/day of extra-virgin olive oil (olive oil group [OOG], n = 69). Triglyceride-glucose (TyG) index (primary outcome) and other markers of glycemic profile were evaluated, and nontraditional anthropometric indexes as well. Diet quality was assessed according to the Alternate Healthy Eating Index (mAHEI).
Results
After adjustment for baseline values, use of antidiabetic drugs and insulin, there were no differences in both glycemic and anthropometric profiles according to groups at the end of the study. PNG improved the quality of the diet in comparison to other groups (final mAHEI scores: CG: 19 ± 7.5; PNG: 26 ± 8; OOG: 18.9 ± 6; P < 0.001).
Conclusions
There was no difference regarding glycemic and anthropometric parameters according to interventions in patients with stable CAD. However, adding pecan nuts to a healthy diet may improve its quality. Further studies must be conducted considering dietary interventions on secondary cardiovascular prevention setting.
Clinical trials identifier number
NCT02202265. First Posted: July 2014; Last Update: September 2020.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
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