Association of magnesium intake with sleep duration and sleep quality: findings from the CARDIA study
Zhang Y, Chen C, Lu L, Knutson KL, Carnethon MR, Fly AD, Luo J, Haas DM, Shikany JM, Kahe K
Sleep · 37 citas
Cómo se estudió
- Diseño
- Estudio de cohortes (clasificado por nuestro filtro de IA)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Posiblemente financiado por la industria
- Universidad u hospital
- Northwestern University
- Universidad u hospital
- University of Minnesota
- Universidad u hospital
- University of Alabama at Birmingham
- Gobierno
- National Institutes of Health
- Empresa
- Kaiser Foundation Research Institute
- Gobierno
- National Heart, Lung, and Blood Institute
- Gobierno
- NHLBI NIH HHS
- Gobierno
- NIH HHS
- Subvenciones
- Northwestern University (HHSN268201800003I); National Heart, Lung, and Blood Institute (HHSN268201800004I); National Heart, Lung, and Blood Institute (R01 HL081572); University of Minnesota (HHSN268201800006I); National Heart, Lung, and Blood Institute (HHSN268201800005I); National Heart, Lung, and Blood Institute (HHSN268201800006I); University of Alabama at Birmingham (HHSN268201800005I); National Heart, Lung, and Blood Institute (HHSN268201800007I); National Heart, Lung, and Blood Institute (HHSN268201800003I); Kaiser Foundation Research Institute (HHSN268201800004I); University of Alabama at Birmingham (HHSN268201800007I); National Institutes of Health (R01HL081572)
Según 8 financiadores declarados.
Publicación
- Publicado
- 2021-11-20 · Sleep · vol. 45 · número 4
- Editorial
- Oxford University Press
- Citado
- 49 citas · más que el 88% de estudios similares · 2.3× el promedio de su campo
- Referencias
- 52 trabajos
- Acceso
- Acceso abierto (copia en repositorio)
- Áreas de investigación
- Magnesium in Health and Disease · Parathyroid Disorders and Treatments · Sleep and related disorders
- Palabras clave
- Quartile, Confounding, Medicine, Odds ratio, Sleep (system call), Longitudinal study, Internal medicine, Generalized estimating equation, Confidence interval, Depression (economics)
- MeSH
- coronary vessels, humans, magnesium, diet, sleep, young adult, sleep wake disorders, sleep quality
10 autores
- Yijia Zhang🇺🇸Columbia University
- Cheng Chen🇺🇸Columbia University
- Liping Lü🇺🇸Columbia University
- Kristen L. Knutson🇺🇸Northwestern University; Circadian (United States)
- Mercedes R. Carnethon🇺🇸Northwestern University
- Alyce D. Fly🇺🇸Ball State University
- Juhua Luo🇺🇸Indiana University Bloomington
- David M. Haas🇺🇸Indiana University School of Medicine; Indiana University – Purdue University Indianapolis
- James M. Shikany🇺🇸University of Alabama at Birmingham
- Ka Kahe🇺🇸 · autor de correspondenciaColumbia University
Resumen
El texto original del estudio, en el idioma en que se publicó.
Study objectives
As an antagonist of calcium (Ca), magnesium (Mg) has been implicated in the regulation of sleep. We aimed to examine the longitudinal associations of Mg intake and Ca-to-Mg intake ratio (Ca:Mg) with sleep quality and duration.
Methods
The study sample consisted of 3,964 participants from the Coronary Artery Risk Development in Young Adults (CARDIA) study. Dietary and supplementary intake of Mg were obtained using the CARDIA Dietary History at baseline (1985-1986), exam years 7 and 20. Self-reported sleep outcomes were measured at years 15 and 20. Sleep quality was rating from 1 (very good) to 5 (very bad). We categorized sleep duration to 9 h. Generalized estimating equation was used to examine the associations of interest as repeated measures at the two time points.
Results
After adjustment for potential confounders, Mg intake was borderline associated with better sleep quality [highest quartile (Q4) vs. intake quartile (Q1): odds ratio (OR) = 1.23; 95% CI = 0.999, 1.50, ptrend = 0.051]. Participants in Q4 were also less likely to have short sleep (<7 h) compared to those in Q1 (OR = 0.64; 95% CI = 0.51, 0.81, ptrend = 0.012). The observed association with short sleep persisted among participants without depressive disorders (Q4 vs. Q1: OR = 0.64; 95% CI = 0.49, 0.82, ptrend < 0.001), but not among individuals with depressive disorder. Ca:Mg was not associated with either outcomes, regardless of depression status.
Conclusions
Mg intake was associated with both sleep outcomes in this longitudinal analysis. Randomized controlled trials with objective measures of sleep are warranted to establish the potential causal inference.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
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