Dietary Magnesium Intake Affects the Association Between Serum Vitamin D and Type 2 Diabetes: A Cross-Sectional Study
Huang W, Ma X, Liang H, Li H, Chen J, Fang L, Yang Q, Zhang Z
Frontiers in nutrition · 37 citas
Cómo se estudió
- Diseño
- Estudio transversal (clasificado por nuestro filtro de IA)
- Estudiado en
- Personas
- Resultado principal
- Eventos clínicos como enfermedad o muerte
Quién lo pagó
- Financiación
- Financiación independiente
- Universidad u hospital
- Guangzhou Medical University
- Gobierno
- Chinese People’s Liberation Army
- Subvenciones
- Guangzhou Medical University (2020-LCYJ-XJS-08)
Según 2 financiadores declarados y la declaración de financiación del texto completo.
Publicación
- Publicado
- 2021-11-25 · Front Nutr · vol. 8 · pág. 763076
- Editorial
- Frontiers Media
- Citado
- 47 citas · más que el 94% de estudios similares · 3.8× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 39 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY
- Áreas de investigación
- Magnesium in Health and Disease · Vitamin D Research Studies · Therapeutic Uses of Natural Elements
- Palabras clave
- Magnesium, Medicine, National Health and Nutrition Examination Survey, Vitamin D and neurology, Type 2 diabetes, Cross-sectional study, Diabetes mellitus, Incidence (geometry), Internal medicine, Vitamin, Dietary Reference Intake, Endocrinology, Nutrient, Environmental health, Population, Chemistry, Mathematics
8 autores
- Wei-Chao Huang🇨🇳Second Affiliated Hospital of Guangzhou Medical University; Guangzhou Medical University
- Xiaoman Ma🇨🇳Third Affiliated Hospital of Guangzhou Medical University; Guangzhou Medical University
- Hualiang Liang🇨🇳Third Affiliated Hospital of Guangzhou Medical University; Guangzhou Medical University
- Haojia Li🇨🇳Third Affiliated Hospital of Guangzhou Medical University; Guangzhou Medical University
- Jiayu Chen🇨🇳Third Affiliated Hospital of Guangzhou Medical University; Guangzhou Medical University
- Liujia Fang🇨🇳Third Affiliated Hospital of Guangzhou Medical University; Guangzhou Medical University
- Qilin Yang🇨🇳 · autor de correspondenciaSecond Affiliated Hospital of Guangzhou Medical University; Guangzhou Medical University
- Zhenhui Zhang🇨🇳 · autor de correspondenciaSecond Affiliated Hospital of Guangzhou Medical University; Guangzhou Medical University
Resumen
El texto original del estudio, en el idioma en que se publicó.
Introduction: Circulating vitamin D concentrations have been associated with the risk of type 2 diabetes (T2D). Magnesium has also been reported to be associated with lower T2D risk. Besides, magnesium is an essential cofactor for vitamin D activation. However, the effect of dietary magnesium intake on the association between vitamin D and the risk of T2D has not been studied comprehensively. Therefore, we designed this cross-sectional study to assess the effect modification of magnesium intake on the association between vitamin D and risk of T2D. Research Design and Methods: The present study analyzed data from the National Health and Nutrition Examination Survey (NHANES) continuously from 2007 to 2014, involving 10,249 participants. By having stratified participants based on magnesium intake category (low magnesium intake Results: In this cross-sectional study, the association of serum vitamin D with the incidence of T2D appeared to differ between the low magnesium intake group and the high magnesium intake group (OR: 0.968, 95%Cl: 0.919-1.02 vs. OR: 0.925, 95%Cl: 0.883-0.97). Furthermore, there was evidence of interaction between vitamin D levels and magnesium intake on decreasing the incidence of T2D (p-value for interaction = 0.001). Conclusions: The results of our study indicated that magnesium intake might affect the association of serum vitamin D with the risk of T2D. Such a finding requires further randomized controlled trials to provide more evidence.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).
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