Ultra-Processed Food Consumption and Adult Diabetes Risk: A Systematic Review and Dose-Response Meta-Analysis
Moradi S, Hojjati Kermani MA, Bagheri R, Mohammadi H, Jayedi A, Lane MM, Asbaghi O, Mehrabani S, Suzuki K
Nutrients · 81 citas
Cómo se estudió
- Diseño
- Metaanálisis (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Eventos clínicos como enfermedad o muerte
- Consumo medido con
- No se indica
Quién lo pagó
- Financiación
- Financiación independiente
Según la declaración de financiación del texto completo.
Publicación
- Publicado
- 2021-12-09 · Nutrients · vol. 13 · número 12 · pág. 4410
- Editorial
- Multidisciplinary Digital Publishing Institute
- Citado
- 122 citas · más que el 96% de estudios similares · 4.8× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 58 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY
- Áreas de investigación
- Consumer Attitudes and Food Labeling · Nutritional Studies and Diet · Obesity, Physical Activity, Diet
- Palabras clave
- Meta-analysis, Medicine, Relative risk, Web of science, Cohort study, Type 2 Diabetes Mellitus, Observational study, Diabetes mellitus, Type 2 diabetes, Random effects model, Scopus, Internal medicine, MEDLINE, Environmental health, Confidence interval, Endocrinology, Biology
- MeSH
- humans, diabetes mellitus, type 2, risk, risk assessment, female, male, fast foods, observational studies as topic
9 autores
- Sajjad Moradi🇮🇷Kermanshah University of Medical Sciences; Niroo Research Institute
- Mohammad Ali Hojjati Kermani🇮🇷Masih Daneshvari Hospital; Shahid Beheshti University of Medical Sciences
- Reza Bagheri🇮🇷University of Isfahan
- Hamed Mohammadi🇮🇷Tehran University of Medical Sciences
- Ahmad Jayedi🇮🇷Tehran University of Medical Sciences
- Melissa M. Lane🇦🇺Barwon Health; Deakin University
- Omid Asbaghi🇮🇷Shahid Beheshti University of Medical Sciences
- Sanaz Mehrabani🇮🇷 · autor de correspondenciaIsfahan University of Medical Sciences
- Katsuhiko Suzuki🇯🇵 · autor de correspondenciaWaseda University
Resumen
El texto original del estudio, en el idioma en que se publicó.
(1) Background: Recent individual studies have demonstrated that consumption of ultra-processed food (UPF) may be related to type two diabetes mellitus (T2DM). We aimed to synthesize the results from these individual studies by conducting an updated systematic review and meta-analysis of observational studies evaluating the association between UPF consumption and the risk of T2DM. (2) Methods: A systematic search was conducted using ISI Web of Science, PubMed/MEDLINE and Scopus electronic databases from inception up to August 2021. Data were extracted from five studies (one cross-sectional study and four cohort studies, totaling 230,526 adults from four different countries). Risk ratios (RR) of pooled results were estimated using a random-effects model. (3) Results: Our results revealed that higher UPF consumption was significantly associated with an increased risk of T2DM (RR = 1.74; 95% CI: 1.36, 2.22; I2 = 68.9%; p n = 5). Linear dose-response analysis indicated that each 10% increase in UPF consumption (kcal/d) was associated with a 15% higher risk of T2DM (RR = 1.15; 95% CI: 1.06, 1.26; I2 = 86.0%; p n = 5) among adults. Non-linear dose-response analysis demonstrated a positive linear association between UPF consumption and T2DM (pnonlinearity = 0.13, pdose-response n = 5) among adults. (4) Conclusions: A higher intake of UPF was significantly associated with an increased risk of T2DM. However, underlying mechanisms remain unknown and future experimental studies are warranted.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).
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