Repercussions of intermittent fasting on the intestinal microbiota community and body composition: a systematic review
Pinto FCS, Silva AAM, Souza SL
Nutrition reviews · 26 citas
Cómo se estudió
- Diseño
- Revisión sistemática (indexado por PubMed)
- Estudiado en
- Personas, más trabajo en animales o laboratorio
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- Conselho Nacional de Desenvolvimento Científico e Tecnológico
- Gobierno
- National Council for Scientific and Technological Development
- Subvenciones
- Conselho Nacional de Desenvolvimento Científico e Tecnológico (132335/2019–0)
Según 2 financiadores declarados.
Publicación
- Publicado
- 2021-11-05 · Nutr Rev · vol. 80 · número 3 · págs. 613–628
- Editorial
- Oxford University Press
- Citado
- 37 citas · más que el 77% de estudios similares · 1.2× el promedio de su campo
- Referencias
- 81 trabajos
- Acceso
- De pago
- Áreas de investigación
- Dietary Effects on Health · Gut microbiota and health · Gastrointestinal motility and disorders
- Palabras clave
- intermittent fasting, gut microbiota, body composition, obesity, alternate-day fasting, time-restricted feeding, Firmicutes/Bacteroidetes ratio, Akkermansia, Lactobacillus, leptin, satiety, insulin sensitivity, circadian rhythm, weight loss
- MeSH
- humans, obesity, weight loss, fasting, body composition, gastrointestinal microbiome
3 autores
- Flaydson Pinto🇧🇷 · autor de correspondenciaUniversidade Federal de Pernambuco
- Amanda A M Silva🇧🇷Universidade de Pernambuco
- Sandra Lopez de Souza🇧🇷Universidade Federal de Pernambuco
Resumen
El texto original del estudio, en el idioma en que se publicó.
Context
Several therapies have been tested for combating weight gain and obesity-related metabolic diseases, and among these therapies, intermittent fasting (IF) has gained a great deal of interest.
Objective
The aim of this study was to provide the reader with a current survey of IF protocols and an understanding of the outcomes found to date in terms of the profile of the intestinal microbiota (IM) in obese organisms.
Data sources
Data were obtained from 4 databases: PubMed, SCOPUS, LILACs, and Web of Science.
Data extraction
Data from studies relating IF protocols to the microbiota and weight loss were extracted using a protocol in START program.
Data analysis
Of the 82 original articles identified from the databases, 35 were eliminated due to duplication, and 32 were excluded due to not meeting the inclusion criteria. Two additional articles found in a new search were added, yielding a total of 17 studies to be included in this review. Among the protocols, alternate-day fasting (ADF) and time-restricted feeding (TRF) were the most common, and they were shown to have different mechanisms of metabolic signaling. TRF influences weight control and biochemical parameters by regulating the circadian system, and improving satiety control systems by acting on leptin secretion. On the other hand, ADF leads to a reduction of ±75% of all energy consumption regardless of dietary composition in addition to promoting hormonal adjustments that promote weight control. Furthermore, both protocols showed the ability to remodel the IM by changing the Firmicutes/Bacteroidetes ratio and increasing the abundance of strains such as Lactobacillus spp. and Akkermansia m. that have a protective effect on metabolism against the effects of weight gain.
Conclusion
In short, the ADF and TRF protocols have a positive effect on the remodeling of the IM and can possibly be used to control body adiposity, improve insulin sensitivity, and achieve other obesity-related metabolic changes.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
Confianza de la comunidad
Cargando…
¿Cuánto confías en los hallazgos de este estudio?
Comentarios
¿Algo está mal aquí?
Señala este estudio si su información, etiquetas o financiación parecen incorrectas. Un editor revisa cada señalamiento.
Información educativa sobre investigación publicada. No es consejo médico ni una recomendación para empezar o dejar nada.