Association between magnesium intake and cognition in US older adults: National Health and Nutrition Examination Survey (NHANES) 2011 to 2014
Tao MH, Liu J, Cervantes D
Alzheimer's & dementia (New York, N. Y.) · 29 citas
Cómo se estudió
- Diseño
- Estudio transversal (clasificado por nuestro filtro de IA)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- National Institutes of Health
- Gobierno
- National Institute on Minority Health and Health Disparities
- Gobierno
- NIMHD NIH HHS
- Subvenciones
- National Institute on Minority Health and Health Disparities (U54MD006882); National Institutes of Health (U54 MD006882)
Según 3 financiadores declarados y la declaración de financiación del texto completo.
Publicación
- Publicado
- 2022-01-01 · Alzheimers Dement (N Y) · vol. 8 · número 1 · pág. e12250
- Editorial
- Elsevier BV
- Citado
- 34 citas · más que el 94% de estudios similares · 3.4× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 51 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY-NC-ND
- Áreas de investigación
- Magnesium in Health and Disease · Parathyroid Disorders and Treatments · Vitamin D Research Studies
- Palabras clave
- National Health and Nutrition Examination Survey, Quartile, Medicine, Confounding, Cognition, Dementia, Vitamin D and neurology, Gerontology, Confidence interval, Cognitive decline, Cross-sectional study, Vitamin, Demography, Environmental health, Internal medicine, Population, Pathology
3 autores
- Meng‐Hua Tao🇺🇸 · autor de correspondenciaUniversity of North Texas; University of North Texas Health Science Center
- Jialiang Liu🇺🇸Temple University Health System; Temple University
- Diana Cervantes🇺🇸University of North Texas; University of North Texas Health Science Center
Resumen
El texto original del estudio, en el idioma en que se publicó.
Introduction
Identifying nutrition- and modifiable lifestyle-based risk factors for cognitive decline and dementia may contribute future primary prevention strategies. This study aimed to evaluate the associations between magnesium intake and cognition in older adults in the United States.
Methods
Based on the National Health and Nutrition Survey (NHANES) between 2011 and 2014, the study included 2508 participants aged 60 years and older. Linear regression models were used to examine the association of total magnesium intake with cognition.
Results
After adjusted demographic and other confounding factors, intakes of energy and total calcium, and serum vitamin D level, higher intake of total magnesium was independently associated with 0.15 higher global cognitive z-score (95% confidence interval, 0.02 to 0.28 for highest vs. lowest quartile, P trend = .037). The positive association of total magnesium intake with global cognition was primarily presented among women, non-Hispanic Whites, and those with sufficient serum vitamin D levels (≥50 nmol/L), although interactions were not significant. There were no clear linear associations for global cognition with serum vitamin D level.
Discussions
Our findings suggest that high magnesium intake alone may improve cognition in older adults, particularly among non-Hispanic Whites and subjects with sufficient levels of serum vitamin D. Further studies are needed to confirm the findings.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY-NC-ND).
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