Effects of nut consumption on blood lipid profile: A meta-analysis of randomized controlled trials
Gunathilake M, Van NTH, Kim J
Nutrition, metabolism, and cardiovascular diseases : NMCD · 10 citas
Cómo se estudió
- Diseño
- Metaanálisis (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
- Consumo medido con
- No se indica
Quién lo pagó
- Financiación
- Financiación independiente
- Universidad u hospital
- National Cancer Center
- Subvenciones
- National Cancer Center (2210990)
Según 1 financiador declarado.
Publicación
- Publicado
- 2022-01-10 · Nutr Metab Cardiovasc Dis · vol. 32 · número 3 · págs. 537–549
- Editorial
- Elsevier BV
- Citado
- 14 citas · más que el 53% de estudios similares · 0.7× el promedio de su campo
- Referencias
- 81 trabajos
- Acceso
- De pago
- Áreas de investigación
- Nuts composition and effects · Nutritional Studies and Diet · Fatty Acid Research and Health
- Palabras clave
- nut consumption, lipid profile, total cholesterol, LDL cholesterol, HDL cholesterol, triglycerides, pistachio, Anacardium occidentale, cardiovascular risk
- MeSH
- humans, nuts, lipids, triglycerides, cholesterol, ldl, cholesterol, hdl, randomized controlled trials as topic
3 autores
- Madhawa Neranjan Gunathilake
- Nhung Thi Hong Van
- Jeongseon Kim · autor de correspondencia
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background & aims
Several randomized controlled trials (RCTs) have assessed the effects of nut consumption on blood lipid profile. The aim of this study was to conduct a meta-analysis to quantitatively estimate the effects of nut consumption on blood lipid profile.
Methods and results
The PubMed, EMBASE, Cochrane Library, and Google Scholar databases were systematically searched to identify RCTs examining the effects of nut intake on blood total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), and triglycerides (TGs) from inception until March 2021. A random-effects model was used to pool standardized mean differences (SMDs) and 95% confidence intervals (CIs). Potential publication bias was assessed using Begg's test and Egger's test. Sensitivity analysis was performed to assess the impact of each individual study on the pooled results. The meta-analysis showed that nut consumption had no significant effect on the blood lipid profile. However, there was a significant reduction in TC (SMD: -2.89, 95% CI: -4.80, -0.98, I2 = 97.4) for pistachio consumption, and cashew consumption significantly increased HDL-C (SMD: 0.24, 95% CI: 0.04, 0.43, I2 = 0.0) compared with that in controls. There was no significant publication bias in the meta-analysis. The sensitivity analysis showed that removing one study at a time did not change the significance of the results.
Conclusion
There was no overall effect of nut consumption on lipid profile, and the results may vary depending on nut type. We found that pistachio consumption may reduce TC levels, while cashew consumption increases HDL-C.
Registry number
PROSPERO CRD42021249147.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
Confianza de la comunidad
Cargando…
¿Cuánto confías en los hallazgos de este estudio?
Comentarios
¿Algo está mal aquí?
Señala este estudio si su información, etiquetas o financiación parecen incorrectas. Un editor revisa cada señalamiento.
Información educativa sobre investigación publicada. No es consejo médico ni una recomendación para empezar o dejar nada.