Egg consumption and risks of all-cause and cause-specific mortality: a dose-response meta-analysis of prospective cohort studies
Yang PF, Wang CR, Hao FB, Peng Y, Wu JJ, Sun WP, Hu JJ, Zhong GC
Nutrition reviews · 12 citas
Etiquetas de revisión
Financiación no declaradaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Metaanálisis (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Eventos clínicos como enfermedad o muerte
- Consumo medido con
- No se indica
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2022-01-14 · Nutr Rev · vol. 80 · número 7 · págs. 1739–1754
- Editorial
- Oxford University Press
- Citado
- 14 citas · más que el 62% de estudios similares · 0.8× el promedio de su campo
- Referencias
- 60 trabajos
- Acceso
- De pago
- Áreas de investigación
- Nutritional Studies and Diet · Antioxidant Activity and Oxidative Stress · Consumer Attitudes and Food Labeling
- Palabras clave
- Medicine, Hazard ratio, Context (archaeology), Prospective cohort study, Meta-analysis, Population, Cohort study, Internal medicine, Relative risk, Demography, Confidence interval, Environmental health, Biology
- MeSH
- humans, neoplasms, cardiovascular diseases, diet, cause of death, risk factors, prospective studies
8 autores
- Pengfei Yang🇨🇳Dalian Medical University; Second Affiliated Hospital of Chongqing Medical University; Chongqing Medical University
- Chunrui Wang🇨🇳Dalian Medical University; Second Affiliated Hospital of Chongqing Medical University; Chongqing Medical University
- Fa‐Bao Hao🇨🇳Qingdao University; Qingdao Women and Children's Hospital
- Yang Peng🇨🇳Chengdu Fifth People's Hospital
- Jingjing Wu🇨🇳Chongqing Public Health Medical Center; Chongqing Medical University
- Weiping Sun🇨🇳Dalian Medical University; Second Affiliated Hospital of Chongqing Medical University; Chongqing Medical University
- Jie‐Jun Hu🇨🇳Dalian Medical University; Second Affiliated Hospital of Chongqing Medical University; Chongqing Medical University
- Guo‐Chao Zhong🇨🇳 · autor de correspondenciaDalian Medical University; Second Affiliated Hospital of Chongqing Medical University; Chongqing Medical University
Resumen
El texto original del estudio, en el idioma en que se publicó.
Context
Current dietary guidelines recommend eggs as a part of a healthy diet. However, whether egg consumption is associated with risk of mortality remains controversial. Moreover, the dose-response association of egg consumption with risk of mortality has not been determined.
Objective
To determine the potential dose-response association of egg consumption with risk of mortality in the general population.
Data sources
The PubMed and Embase databases were searched for publications meeting eligibility criteria through November 2021.
Data extraction
Required data were extracted by 1 reviewer and then checked for accuracy by another reviewer. A random-effects dose-response meta-regression model was used to calculate the pooled risk estimates. A restricted cubic spline model was used to test nonlinearity. The certainty of evidence was assessed using the GRADE system.
Data analysis
Nineteen prospective cohort studies, involving 1 737 893 participants, were included. The pooled hazard ratios for an increase of 1 egg/d were 1.08 (95%CI, 1.01-1.15) for all-cause mortality, 1.07 (95%CI, 0.97-1.18) for cardiovascular disease-caused mortality, and 1.16 (95%CI, 1.04-1.30) for cancer-caused mortality. The certainty of evidence for these observations was rated as very low. Nonlinear dose-response associations were found for egg consumption and all-cause, cardiovascular disease-caused, and cancer-caused mortality. Moreover, the positive association between egg consumption and all-cause mortality was more pronounced in studies with adjustment for blood cholesterol-related covariates than those without (Pinteraction = 0.011).
Conclusions
Greater amount of egg consumption confers higher risks of death from all causes, cardiovascular disease, and canc er in a nonlinear dose-response pattern. These findings should be treated with caution and need to be confirmed by future studies.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
Confianza de la comunidad
Cargando…
¿Cuánto confías en los hallazgos de este estudio?
Comentarios
¿Algo está mal aquí?
Señala este estudio si su información, etiquetas o financiación parecen incorrectas. Un editor revisa cada señalamiento.
Información educativa sobre investigación publicada. No es consejo médico ni una recomendación para empezar o dejar nada.