Dietary Magnesium Intake Modifies the Association Between Vitamin D and Systolic Blood Pressure: Results From NHANES 2007-2014
Huang W, Ma X, Chen Y, Zheng J, Li H, Nizhamu A, Hong Q, Guo X
Frontiers in nutrition · 14 citas
Cómo se estudió
- Diseño
- Estudio transversal (clasificado por nuestro filtro de IA)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- Chinese People’s Liberation Army
Según 1 financiador declarado y la declaración de financiación del texto completo.
Publicación
- Publicado
- 2022-02-24 · Front Nutr · vol. 9 · pág. 829857
- Editorial
- Frontiers Media
- Citado
- 15 citas · más que el 79% de estudios similares · 1.4× el promedio de su campo
- Referencias
- 38 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY
- Áreas de investigación
- Magnesium in Health and Disease · Vitamin D Research Studies · Parathyroid Disorders and Treatments
- Palabras clave
- National Health and Nutrition Examination Survey, Blood pressure, Medicine, Magnesium, Vitamin D and neurology, Vitamin, Internal medicine, Dietary Reference Intake, Endocrinology, Vitamin C, Nutrient, Chemistry, Population, Environmental health
8 autores
- Wei-Chao Huang🇨🇳Second Affiliated Hospital of Guangzhou Medical University; Third Affiliated Hospital of Guangzhou Medical University; Guangzhou Medical University
- Xiaoman Ma🇨🇳Third Affiliated Hospital of Guangzhou Medical University; Guangzhou Medical University
- Yue Chen🇨🇳Second Affiliated Hospital of Guangzhou Medical University; Third Affiliated Hospital of Guangzhou Medical University; Guangzhou Medical University
- Jiayi Zheng🇨🇳Second Affiliated Hospital of Guangzhou Medical University; Third Affiliated Hospital of Guangzhou Medical University; Guangzhou Medical University
- Haojia Li🇨🇳Third Affiliated Hospital of Guangzhou Medical University; Guangzhou Medical University
- Ayinigaer Nizhamu🇨🇳Second Affiliated Hospital of Guangzhou Medical University; Third Affiliated Hospital of Guangzhou Medical University; Guangzhou Medical University
- Qingting Hong🇨🇳Third Affiliated Hospital of Guangzhou Medical University; Guangzhou Medical University
- Xu‐Guang Guo🇨🇳 · autor de correspondenciaThird Affiliated Hospital of Guangzhou Medical University; Guangzhou Medical University
Resumen
El texto original del estudio, en el idioma en que se publicó.
Introduction
Although the association between blood pressure and vitamin D has been well studied, the effects of dietary magnesium intake on this relationship are still unclear. Thus, this study aimed to determine the effects of dietary magnesium intake on the association between vitamin D and blood pressure.
Methods
The present study analyzed data from the continuous the National Health and Nutrition Examination Survey (NHANES) 2007-2014. We included 8,799 participants aged 20 years or older. Multivariable linear regression was performed to assess the association between vitamin D and systolic blood pressure (SBP) and diastolic blood pressure (DBP). Dietary magnesium intake was stratified by low magnesium intake (<299 mg/d) and high magnesium intake (≥299 mg/d). Effect modification by dietary magnesium intake was assessed through interaction tests between vitamin D and SBP in the multivariable linear regression.
Results
In this cross-sectional study, we found that vitamin D was negatively related to SBP, but not to DBP. The relationship between vitamin D and SBP was different in the low and high magnesium intake group (β: -0.25 95%Cl: -0.4~0.07 vs β: -0.32 95%Cl: -0.52~-0.12). Furthermore, magnesium intake significantly modified the negative relationship between vitamin D and SBP in most of the models.
Conclusion
Our research showed that magnesium and vitamin D have an interactive effect in reducing SBP, which may have great importance for clinical medication.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).
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