Bladder volume reproducibility after water consumption in patients with prostate cancer undergoing radiotherapy: A systematic review and meta-analysis
Chen HH, Lin PT, Kuo LT, Lin KS, Fang CC, Chi CC
Biomedical journal · 13 citas
Cómo se estudió
- Diseño
- Metaanálisis (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
Según la declaración de financiación del texto completo.
Publicación
- Publicado
- 2020-11-05 · Biomed J · vol. 44 · número 6 · págs. S226–S234
- Editorial
- Elsevier BV
- Citado
- 19 citas · más que el 70% de estudios similares · 0.6× el promedio de su campo
- Referencias
- 35 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY-NC-ND
- Áreas de investigación
- Advanced Radiotherapy Techniques · Prostate Cancer Diagnosis and Treatment · Radiation Therapy and Dosimetry
- Palabras clave
- Medicine, Reproducibility, Meta-analysis, Randomized controlled trial, Radiation therapy, Bladder cancer, Prostate cancer, Prostate, Confidence interval, Cancer, Internal medicine
- MeSH
- humans, prostatic neoplasms, water, reproducibility of results, drinking, male, urinary bladder, randomized controlled trials as topic
6 autores
- Hsiao-Hsuan Chen🇹🇼Chiayi Chang Gung Memorial Hospital
- Pei-Tzu Lin🇹🇼Chiayi Chang Gung Memorial Hospital
- Liang‐Tseng Kuo🇹🇼Chiayi Chang Gung Memorial Hospital
- Kun-Sheng Lin🇹🇼Chiayi Chang Gung Memorial Hospital
- Chiung-Chen Fang🇹🇼Chiayi Chang Gung Memorial Hospital
- Ching‐Chi Chi🇹🇼 · autor de correspondenciaChang Gung University; Chang Gung Memorial Hospital; Linkou Chang Gung Memorial Hospital
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background
To minimize toxicity due to radiotherapy in patients with prostate cancer, high bladder volume reproducibility is essential. Water consumption is often used to increase bladder volume reproducibility, but the optimal amount of water required to be consumed remains unclear. We aimed to analyzed the relationship between water consumption and bladder volume reproducibility in patients undergoing radiotherapy for prostate cancer.
Methods
We conducted a systematic review and meta-analysis of randomized controlled trials and cohort studies that assessed bladder volume change after water consumption in patients with prostate cancer undergoing radiotherapy. MEDLINE, Embase, and Cochrane Central Register of Controlled Trials were searched for relevant studies published from database inception up until July 4, 2020. The Newcastle-Ottawa Scale was used to evaluate the risk of bias in the included studies. The outcome was the mean difference (MD) of bladder volume after water consumption, evaluated through meta-analysis using a random-effects model.
Results
Ten cohort studies and one randomized controlled trial with a total of 417 patients were included. For 300-400 ml water consumption, the bladder volume MD between during treatment and at computer tomography-simulation (95% confidence interval [CI]) was -11.97 (-51.68 to 27.74), was -45.99 (-82.85 to -9.13) for 500-540 ml water consumption and -45.92 (-78.86 to -12.98) for water consumption until full-bladder sensation was reached.
Conclusion
Consuming 300-400 ml of water potentially leads to the best bladder volume reproducibility; moreover, the higher the water consumption volume, the lower the bladder volume reproducibility.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY-NC-ND).
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