Ultraprocessed food consumption and kidney function decline in a population-based cohort in the Netherlands
Cai Q, Duan MJ, Dekker LH, Carrero JJ, Avesani CM, Bakker SJL, de Borst MH, Navis GJ
The American journal of clinical nutrition · 46 citas
Etiquetas de revisión
Cuestionario de frecuencia de consumoDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Estudio de cohortes (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Eventos clínicos como enfermedad o muerte
- Consumo medido con
- Cuestionario de frecuencia de consumo
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- European Commission
- Gobierno
- Ministerie van Volksgezondheid, Welzijn en Sport
- Universidad u hospital
- Universitair Medisch Centrum Groningen
- Universidad u hospital
- University Medical Center Groningen
- Gobierno
- Marie Skłodowska-Curie
- Gobierno
- Dutch Ministry of Economic Affairs
- Gobierno
- Dutch Ministry of Health, Welfare and Sport
- Gobierno
- European Union
- Subvenciones
- European Commission (HORIZON2020); European Commission (754425)
Según 8 financiadores declarados y la declaración de financiación del texto completo.
Publicación
- Publicado
- 2022-03-25 · Am J Clin Nutr · vol. 116 · número 1 · págs. 263–273
- Editorial
- Elsevier BV
- Citado
- 59 citas · más que el 99% de estudios similares · 9.5× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 68 trabajos
- Acceso
- Acceso abierto (revista híbrida) · CC-BY-NC
- Áreas de investigación
- Consumer Attitudes and Food Labeling · Nutrition, Genetics, and Disease · Nutritional Studies and Diet
- Palabras clave
- Consumption (sociology), Cohort, Food consumption, Population, Environmental health, Demography, Medicine, Economics, Agricultural economics, Internal medicine, Sociology
- MeSH
- kidney, humans, diet, cohort studies, prospective studies, netherlands, renal insufficiency, chronic, fast foods
8 autores
- Qingqing Cai🇳🇱🇨🇳🇺🇸 · autor de correspondenciaUniversity Medical Center Groningen; University of Groningen; Key Laboratory of Guangdong Province; Nanfang Hospital; National Clinical Research; Southern Medical University
- Ming-Jie Duan🇳🇱University Medical Center Groningen; University of Groningen
- Louise H. Dekker🇳🇱University Medical Center Groningen; University of Groningen
- Juan Jesús Carrero🇸🇪Karolinska Institutet
- Carla María Avesani🇸🇪Karolinska Institutet
- Stephan J. L. Bakker🇳🇱University Medical Center Groningen; University of Groningen
- Martin H. de Borst🇳🇱University Medical Center Groningen; University of Groningen
- Gerjan J Navis🇳🇱University Medical Center Groningen; University of Groningen
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background
Ultraprocessing makes food products more convenient, appealing, and profitable. Recent studies show that high ultraprocessed food (UPF) intake is associated with cardiometabolic diseases.
Objectives
The aim of this study is to investigate the association between UPF consumption and risks of kidney function decline in the general population.
Methods
In a prospective, general population-based Lifelines cohort from Northern Netherlands, 78,346 participants free of chronic kidney disease (CKD) at baseline responded to a 110-item FFQ. We used a multivariable regression analysis to study the associations of the proportion (in grams/day) of UPFs in the total diet with a composite kidney outcome [incident CKD or a ≥30% estimated glomerular filtration rate (eGFR) decline relative to baseline] and annual change in eGFR.
Results
On average, 37.7% of total food intake came from UPFs. After 3.6 ± 0.9 years of follow-up, 2470 participants (3.2%) reached the composite kidney outcome. Participants in the highest quartile of UPF consumption were associated with a higher risk of the composite kidney outcome (OR, 1.27; 95% CI, 1.09-1.47; P = 0.003) compared with those in the lowest quartile, regardless of their macro- or micronutrient intake or diet quality. Participants in the highest quartile had a more rapid eGFR decline (β, -0.17; 95% CI, -0.23 to -0.11; P < 0.001) compared with those in the lowest quartile. Associations were generally consistent across different subgroups.
Conclusions
Higher UPF consumption was associated with a higher risk of a composite kidney outcome (incident CKD or ≥30% eGFR decline) and a more rapid eGFR decline in the general population, independent of confounders and other dietary indices.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY-NC).
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