Egg Consumption and Risk of All-Cause and Cause-Specific Mortality: A Systematic Review and Dose-Response Meta-analysis of Prospective Studies
Mousavi SM, Zargarzadeh N, Rigi S, Persad E, Pizarro AB, Hasani-Ranjbar S, Larijani B, Willett WC, Esmaillzadeh A
Advances in nutrition (Bethesda, Md.) · 26 citas
Etiquetas de revisión
Financiación no declaradaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Metaanálisis (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Eventos clínicos como enfermedad o muerte
- Consumo medido con
- No se indica
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2022-04-09 · Adv Nutr · vol. 13 · número 5 · págs. 1762–1773
- Editorial
- Elsevier BV
- Citado
- 31 citas · más que el 80% de estudios similares · 1.5× el promedio de su campo
- Referencias
- 104 trabajos
- Acceso
- Acceso abierto (revista híbrida) · CC-BY-NC-ND
- Áreas de investigación
- Nutritional Studies and Diet · Consumer Attitudes and Food Labeling · Obesity, Physical Activity, Diet
- Palabras clave
- Medicine, Relative risk, Meta-analysis, Population, Cohort study, Internal medicine, Prospective cohort study, MEDLINE, Confidence interval, Environmental health, Biology
- MeSH
- humans, neoplasms, cardiovascular diseases, coronary disease, cause of death, prospective studies, stroke
9 autores
- Seyed Mohammad Mousavi🇮🇷Obesity and Eating Habits Research Center; Tehran University of Medical Sciences
- Nikan Zargarzadeh🇮🇷Tehran University of Medical Sciences
- Somaye Rigi🇮🇷Tehran University of Medical Sciences
- Emma Persad🇦🇹Universität für Weiterbildung Krems
- Ana Beatriz Pizarro🇨🇴Fundación Valle del Lili
- Shirin Hasani‐Ranjbar🇮🇷Obesity and Eating Habits Research Center; Tehran University of Medical Sciences
- Bagher A. Larijani🇮🇷Tehran University of Medical Sciences
- Walter Churchill Willett🇺🇸Brigham and Women's Hospital; Harvard University
- Ahmad Esmaillzadeh🇮🇷 · autor de correspondenciaIsfahan University of Medical Sciences; Obesity and Eating Habits Research Center; Tehran University of Medical Sciences
Resumen
El texto original del estudio, en el idioma en que se publicó.
The association between egg consumption and mortality is extremely debatable. This study aimed to investigate the potential dose-response association of egg consumption with risk of mortality from all causes and cause-specific in the general population. The primary comprehensive literature search was conducted in PubMed/Medline, Scopus, ISI Web of Science, and Embase up to March 2021, as well as reference lists of relevant original papers and key journals. We calculated summary RRs and their 95% CIs for the highest and lowest categories, as well as the linear trend estimation of egg intake, using the random-effects model. Thirty-three (32 publications) cohort studies were included. These studies enrolled 2,216,720 participants and recorded 232,408 deaths from all causes. Comparing highest versus lowest egg intake categories was not associated with the risk of mortality from all causes (RR: 1.02; 95% CI: 0.94, 1.11; n = 25), cardiovascular disease (CVD) (RR: 1.04; 95% CI: 0.87, 1.23, n = 11), coronary heart disease (CHD) (RR: 0.98; 95% CI: 0.84, 1.16; n = 10), stroke (RR: 0.81; 95% CI: 0.64, 1.02; n = 9), and respiratory disease (RR: 0.96; 95% CI: 0.53, 1.71; n = 3); however, it was associated with a higher risk of cancer mortality (RR: 1.20; 95% CI: 1.04, 1.39; n = 13). In the linear dose-response analysis, an additional intake of 1 egg per week was associated with a 2% and 4% increased risk of all-cause and cancer mortality, respectively, and a 4% decreased risk of stroke mortality. The certainty of the evidence was rated as low to moderate. Higher egg consumption was not associated with an increased risk of mortality from all causes, CVD, CHD, stroke, or respiratory disease, whereas an elevated risk was observed for cancer mortality. These findings suggest that eggs be consumed in low to moderate amounts (≤1 egg/d) as part of a healthy diet.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY-NC-ND).
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