Pulsatile flow in venous perforators of the lower limb
Thomas KN, Gibbons TD, Campbell HA, Cotter JD, van Rij AM
American journal of physiology. Regulatory, integrative and comparative physiology · 6 citas
Etiquetas de revisión
Solo mecanismosDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Ensayo clínico controlado (clasificado por nuestro filtro de IA)
- Estudiado en
- Personas
- Resultado principal
- Solo mecanismos
Quién lo pagó
- Financiación
- Financiación independiente
- Sin clasificar
- None required
Según 1 financiador declarado.
Publicación
- Publicado
- 2022-05-03 · Am J Physiol Regul Integr Comp Physiol · vol. 323 · número 1 · págs. R59–R67
- Editorial
- American Physiological Society
- Citado
- 11 citas · más que el 78% de estudios similares · 1.2× el promedio de su campo
- Referencias
- 47 trabajos
- Acceso
- De pago
- Áreas de investigación
- Thermoregulation and physiological responses · Diagnosis and Treatment of Venous Diseases · Climate Change and Health Impacts
- Palabras clave
- Pulsatile flow, Medicine, Blood flow, Ultrasound, Microcirculation, Diastole, Ankle, Cardiac cycle, Vein, Core (optical fiber), Anatomy, Biomedical engineering, Perfusion, Hemodynamics, Cardiology, Internal medicine, Blood pressure, Materials science, Radiology
- MeSH
- lower extremity, leg, humans, water, blood flow velocity, pulsatile flow
5 autores
- Kate Nicole Thomas🇳🇿 · autor de correspondenciaUniversity of Otago
- Travis Dylan Gibbons🇨🇦🇳🇿University of British Columbia; University of British Columbia, Okanagan Campus; University of Otago
- Holly A. Campbell🇳🇿University of Otago
- James David Cotter🇳🇿University of Otago
- André M. van Rij🇳🇿University of Otago
Resumen
El texto original del estudio, en el idioma en que se publicó.
Teaching traditionally asserts that the arterial pressure pulse is dampened across the capillary bed to the extent that pulsatility is nonexistent in the venous circulation of the lower limbs. Herein, we present evidence of transmission of arterial pulsations across the capillary network into perforator veins in the lower limbs of healthy, heat-stressed humans. Perforator veins are connections from the superficial veins that drain into the deep veins. When assessed using ultrasound at rest, they infrequently demonstrate flow, and a pulsatile flow waveform is not described. We investigated perforator vein pulsatility in 10 young, healthy volunteers who underwent passive heating by +2°C core body temperature via a hot-water-perfused suit, and 5 who also underwent active heating by +2°C via low-intensity cycling while wearing the hot-water-perfused suit. At +0.5°C increments in temperature, blood velocity in an ankle perforator vein was measured using duplex ultrasound. In all perforators with heating, sustained flow was demonstrated, with a pulsatile waveform that was synchronous with the cardiac cycle. The maximum velocity was 30 ± 13 cm/s with passive heating and approximately half with active heating (P = 0.04). The small veins of the skin at the ankle also demonstrated increased perfusion with pulsatility, seen with low-velocity microvascular imaging technology. We consider explanations for this pulsatility and conclude that it is propagated from the arterial inflow through the skin microcirculation as a result of increased dilatation and flow volume and that this is a normal response to increased skin blood flow.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
Confianza de la comunidad
Cargando…
¿Cuánto confías en los hallazgos de este estudio?
Comentarios
¿Algo está mal aquí?
Señala este estudio si su información, etiquetas o financiación parecen incorrectas. Un editor revisa cada señalamiento.
Información educativa sobre investigación publicada. No es consejo médico ni una recomendación para empezar o dejar nada.