Association of dietary cholesterol and dyslipidemia in Chinese health examinees
Pan J, Han W, Jiang Y, Wu J, Zhou X
Journal of health, population, and nutrition · 6 citas
Etiquetas de revisión
Cuestionario de frecuencia de consumoFinanciación no declaradaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Estudio transversal (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
- Consumo medido con
- Cuestionario de frecuencia de consumo
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2022-05-03 · J Health Popul Nutr · vol. 41 · número 1 · pág. 15
- Editorial
- BioMed Central
- Citado
- 7 citas · más que el 79% de estudios similares · 1.4× el promedio de su campo
- Referencias
- 26 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY
- Áreas de investigación
- Nutritional Studies and Diet · Cholesterol and Lipid Metabolism · Diabetes, Cardiovascular Risks, and Lipoproteins
- Palabras clave
- Dyslipidemia, Medicine, Confounding, Cholesterol, Dietary Cholesterol, Cross-sectional study, Environmental health, Internal medicine, Diabetes mellitus, Endocrinology, Pathology
- MeSH
- humans, cholesterol, dietary, cross-sectional studies, china, female, male, dyslipidemias, asian people
5 autores
- Junqiang Pan🇨🇳 · autor de correspondenciaXian Central Hospital; First Hospital of Xi'an
- Wenqi Han🇨🇳Shanxi Medical University; Shanxi Provincial People’s Hospital
- Yongrong Jiang🇨🇳First Affiliated Hospital of Xi'an Jiaotong University
- Jine Wu🇨🇳First Affiliated Hospital of Xi'an Jiaotong University
- Xin Zhou🇨🇳First Affiliated Hospital of Xi'an Jiaotong University
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background
The association between dietary cholesterol consumption and dyslipidemia is still in controversy. The study aims to evaluate whether dietary cholesterol intake associated with dyslipidemia and its components in Chinese health examinees.
Methods
A large-scale cross-sectional study was conducted among health examinees of in Shaanxi province. Totally of 8358 participants (3677 male and 4681 female) were included. Dietary cholesterol intake was assessed by validated food frequency questionnaire. Multivariable regression and restricted cubic spline models were used to capture the linear and non-linear association between dietary cholesterol and dyslipidemia.
Results
A total of 2429 (29.1%) subjects were newly diagnosed of dyslipidemia, the prevalence was 29.2% in male and 27.7% in female. Mean intake of dietary cholesterol was 213.7 mg/day. After adjusting for all potential confounders including demographics information and lifestyles, higher cholesterol consumption was related to lower risk of dyslipidemia, the ORs (95% CIs) across Q2 to Q4 group were 0.87 (0.60-1.26), 0.80 (0.55-1.18) and 0.61 (0.41-0.91) in female. With further controlling for nutrients principal components, a null association was observed between dietary cholesterol and dyslipidemia and serum lipids, regardless of gender. Results of restricted cubic splines showed that the risk of dyslipidemia decreased slowly until around 300 mg/day in men and 200 mg/day in women, although the non-linear association was not significant.
Conclusions
The study suggested that dietary cholesterol consumption was not associated with dyslipidemia or serum lipids in Chinese health examinees, although a decreased risk was observed before the threshold points.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).
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