Plasma Amino Acid Appearance and Status of Appetite Following a Single Meal of Red Meat or a Plant-Based Meat Analog: A Randomized Crossover Clinical Trial
Pham T, Knowles S, Bermingham E, Brown J, Hannaford R, Cameron-Smith D, Braakhuis A
Current developments in nutrition · 31 citas
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Cómo se estudió
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- Ensayo controlado aleatorizado (clasificado por nuestro filtro de IA)
- Estudiado en
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- Resultado principal
- Marcadores de salud y funcionamiento
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Quién lo pagó
- Financiación
- Financiación independiente
Según la declaración de financiación del texto completo.
Publicación
- Publicado
- 2022-04-28 · Curr Dev Nutr · vol. 6 · número 5 · pág. nzac082
- Editorial
- Elsevier BV
- Citado
- 47 citas · más que el 98% de estudios similares · 6.7× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 62 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY-NC-ND
- Áreas de investigación
- Agriculture Sustainability and Environmental Impact · Meat and Animal Product Quality · Nutritional Studies and Diet
- Palabras clave
- Postprandial, Crossover study, Meal, Appetite, Food science, Amino acid, Pasture, Animal science, Biology, Chemistry, Medicine, Biotechnology, Biochemistry, Insulin, Internal medicine, Agronomy
7 autores
- Toan Thanh Pham🇳🇿 · autor de correspondenciaUniversity of Auckland
- Scott O. Knowles🇳🇿AgResearch
- Emma N. Bermingham🇳🇿AgResearch
- Julie. E. Brown🇳🇿University of Auckland
- Rina Hannaford🇳🇿AgResearch
- David Cameron‐Smith🇦🇺University of Newcastle Australia
- Andrea Jane Braakhuis🇳🇿University of Auckland
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background
Red meat is a nutrient-dense food and a dietary staple. A new generation of plant-based meat analogs (PBMAs) have been designed to mimic the experience of eating meat, but there is limited evidence about their digestive efficacy and nutritional quality.
Objectives
We compared the postprandial digestive response of a single meal containing meat commercially raised in New Zealand, including lamb, on-farm pasture-raised beef (Pasture), or grain-finished beef (Grain) with a PBMA (Beyond Burger; Beyond Meat) sold through consumer retail. The primary outcome was the appearance of amino acids in plasma. Secondary outcomes included glucose and insulin, appetite assessment, and anthropometry.
Methods
Thirty healthy men (20-34 y) participated in a double-blinded randomized crossover trial. Each consumed 1 of the 4 test meals on 4 occasions separated by a washout period of at least 1 wk, following an overnight fast. The meal was a burrito-style wrap containing meat or PBMAs, vegetables, salsa, and seasonings in a flour tortilla. The amount of Pasture, Grain, Lamb, or BB was 220 g raw (∼160 g cooked). Venous blood samples were collected over 4 h. Appetite and hunger status was scored with visual analog scales.
Results
Pre-meal amino acid concentrations in plasma did not differ by group (P > 0.9), although several nonessential amino acids differed strongly according to participant BMI. Postprandial amino acids peaked at 2-3 h in all groups. The BB meal produced significantly lower plasma concentrations of total, essential, branched-chain, and non-proteogenic amino acids than the Lamb, Pasture, or Grain meals, based on AUC. There were no significant differences between meal groups in scores for hunger, fullness, or cravings.
Conclusions
Red meat meals exhibited greater bioavailability of amino acids compared with the PBMA (BB). Pasture versus Grain origins of the beef had little influence on participants' responses. This trial was registered at ClinicalTrials.gov as NCT04545398.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).
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