Dietary Magnesium Intake Ameliorates the Association Between Household Pesticide Exposure and Type 2 Diabetes: Data From NHANES, 2007-2018
Huang J, Hu L, Yang J
Frontiers in nutrition · 11 citas
Cómo se estudió
- Diseño
- Estudio transversal (clasificado por nuestro filtro de IA)
- Estudiado en
- Personas
- Resultado principal
- Eventos clínicos como enfermedad o muerte
Quién lo pagó
- Financiación
- Financiación independiente
Según la declaración de financiación del texto completo.
Publicación
- Publicado
- 2022-05-20 · Front Nutr · vol. 9 · pág. 903493
- Editorial
- Frontiers Media
- Citado
- 26 citas · más que el 90% de estudios similares · 2.6× el promedio de su campo
- Referencias
- 41 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY
- Áreas de investigación
- Magnesium in Health and Disease · Protein Kinase Regulation and GTPase Signaling · Parathyroid Disorders and Treatments
- Palabras clave
- Medicine, National Health and Nutrition Examination Survey, Type 2 diabetes, Diabetes mellitus, Environmental health, Population, Odds ratio, Pesticide, Toxicology, Internal medicine, Endocrinology, Biology
3 autores
- Jungao Huang🇨🇳Gansu Provincial Maternal and Child Health Hospital; Xi'an Jiaotong University
- Liqin Hu🇨🇳Gansu Provincial Maternal and Child Health Hospital
- Juan Yang🇨🇳 · autor de correspondenciaXi'an Jiaotong University
Resumen
El texto original del estudio, en el idioma en que se publicó.
Aims/hypothesis
This study aimed to explore whether household pesticide exposure in the general population increased the risk of developing type 2 diabetes and whether intake of dietary magnesium could lower type 2 diabetes from household pesticide exposure.
Methods
For this cross-sectional study, we obtained the data of 9,187 United States adults from the National Health and Nutrition Examination Surveys, 2007-2018. Participants were subdivided into two groups based on the amount of daily dietary magnesium in the population: low group: <175 mg/day and high group: ≥175 mg/day. Using multivariable logistic regression analysis, we evaluated the relationship between pesticide exposure in the home and type 2 diabetes.
Results
Compared to those unexposed at home, individuals who were exposed to pesticides in their households had a relatively higher odds ratio for type 2 diabetes (OR = 1.22, 95% CI: 1.04-1.44). The association of pesticide exposure in the home with the incidence of type 2 diabetes was different for low and high dietary magnesium groups, OR = 1.66, 95% Cl: 1.19-2.33 vs. OR = 1.1, 95% Cl: 0.92-1.32, respectively. An interaction (P = 0.035) between household pesticide exposure and magnesium intake, suggested that high dietary magnesium intake may reduce the risk of developing type 2 diabetes from pesticide exposure.
Conclusions
Household pesticide exposure in the general population is associated with an elevated risk of type 2 diabetes. We report for the first time possible clinical relevance in that high magnesium intake may ameliorate the increased risk of type 2 diabetes from pesticide exposure.
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