Consumption of whole grains and risk of type 2 diabetes: A comprehensive systematic review and dose-response meta-analysis of prospective cohort studies
Ghanbari-Gohari F, Mousavi SM, Esmaillzadeh A
Food science & nutrition · 24 citas
Cómo se estudió
- Diseño
- Metaanálisis (clasificado por nuestro filtro de IA)
- Estudiado en
- Personas
- Resultado principal
- Eventos clínicos como enfermedad o muerte
- Consumo medido con
- No se indica
Quién lo pagó
- Financiación
- Financiación independiente
Según la declaración de financiación del texto completo.
Publicación
- Publicado
- 2022-03-10 · Food Sci Nutr · vol. 10 · número 6 · págs. 1950–1960
- Editorial
- Wiley
- Citado
- 45 citas · más que el 88% de estudios similares · 2.3× el promedio de su campo
- Referencias
- 67 trabajos
- Acceso
- Acceso abierto (revista híbrida) · CC-BY
- Áreas de investigación
- Nutritional Studies and Diet · Food composition and properties · Nutrition and Health in Aging
- Palabras clave
- Medicine, Type 2 diabetes, Meta-analysis, Relative risk, Prospective cohort study, Confidence interval, Observational study, Cohort study, Randomized controlled trial, Internal medicine, MEDLINE, Random effects model, Diabetes mellitus, Demography, Endocrinology, Biology
3 autores
- Faezeh Ghanbari‐Gohari🇮🇷Tehran University of Medical Sciences
- Seyed Mohammad Mousavi🇮🇷Obesity and Eating Habits Research Center; Tehran University of Medical Sciences
- Ahmad Esmaillzadeh🇮🇷 · autor de correspondenciaIsfahan University of Medical Sciences; Obesity and Eating Habits Research Center; Tehran University of Medical Sciences
Resumen
El texto original del estudio, en el idioma en que se publicó.
This study aimed to quantitatively summarize earlier findings on the association between whole grain (WG) intake and type 2 diabetes (T2D) risk. We searched related keywords on PubMed/Medline, Scopus, and Google Scholar up to October 2021. Prospective observational studies investigating the association between WG intake and risk of T2D were included. The random-effects model calculates the summary relative risks by contrasting categories and linear and nonlinear dose-response associations. Eleven prospective cohort studies, including 463,282 participants and 37,249 type 2 diabetes incidents, were analyzed. The pooled relative risk (RR) for the highest versus the lowest WG intake category indicated a 21% decrease in T2D risk (95% confidence interval (CI): 0.73-0.85, I 2 = 77%). Each additional 50 grams WG consumption per day was associated with a 23% reduced risk of T2D. The nonlinear association of WG and T2D revealed that 60 grams WG intake per day would give the highest benefit to prevent T2D (Pnonlinearity < 0.001). The findings were not affected by any individual study. No evidence of publication bias was documented. In conclusion, a high intake of WG was associated with a lower risk of T2D. Randomized controlled trials are needed to confirm our results.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).
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