Associations of the Dietary Magnesium Intake and Magnesium Depletion Score With Osteoporosis Among American Adults: Data From the National Health and Nutrition Examination Survey
Wang J, Xing F, Sheng N, Xiang Z
Frontiers in nutrition · 29 citas
Cómo se estudió
- Diseño
- Estudio transversal (clasificado por nuestro filtro de IA)
- Estudiado en
- Personas
- Resultado principal
- Eventos clínicos como enfermedad o muerte
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- National Natural Science Foundation of China
- Gobierno
- Department of Science and Technology of Sichuan Province
- Universidad u hospital
- Sichuan University
- Universidad u hospital
- West China Hospital, Sichuan University
- Subvenciones
- Department of Science and Technology of Sichuan Province (2022YFS0099); West China Hospital, Sichuan University (2019HXFH041); National Natural Science Foundation of China (31870961); Sichuan University (2019HXFH041); National Natural Science Foundation of China (2019HXFH041)
Según 4 financiadores declarados y la declaración de financiación del texto completo.
Publicación
- Publicado
- 2022-05-31 · Front Nutr · vol. 9 · pág. 883264
- Editorial
- Frontiers Media
- Citado
- 34 citas · más que el 93% de estudios similares · 3.2× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 38 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY
- Áreas de investigación
- Magnesium in Health and Disease · Parathyroid Disorders and Treatments · Bone health and osteoporosis research
- Palabras clave
- National Health and Nutrition Examination Survey, Osteoporosis, Medicine, Confidence interval, Logistic regression, Odds ratio, Linear regression, Demography, Bayesian multivariate linear regression, Internal medicine, Gerontology, Environmental health, Population, Statistics, Mathematics
4 autores
- Jie Wang🇨🇳Sichuan University; West China Hospital of Sichuan University
- Fei Xing🇨🇳Sichuan University; West China Hospital of Sichuan University
- Ning Sheng🇨🇳Sichuan University; West China Hospital of Sichuan University
- Zhou Xiang🇨🇳 · autor de correspondenciaSichuan University; West China Hospital of Sichuan University
Resumen
El texto original del estudio, en el idioma en que se publicó.
Objectives
The study aimed to explore the associations between dietary magnesium (Mg) intake and magnesium depletion score (MDS) among American adults with osteoporosis.
Methods
The continuous data from the National Health and Nutrition Examination Survey 2005-2006, 2007-2008, 2009-2010, 2013-2014, and 2017-2018 were merged to ensure a large and representative sample and a total of 14,566 participants were enrolled for the analysis. The weighted multivariate linear regression model was performed to assess the linear relationship between dietary Mg intake and osteoporosis. Further, the non-linear relationship was also characterized by smooth curve fitting (SCF) and weighted generalized additive model (GAM). In addition, the odds ratios (ORs) and 95% confidence intervals (95% CIs) for associations between the MDS and osteoporosis were assessed by weighted logistic regression models.
Results
After adjusting all covariates, the weighted multivariable linear regression models demonstrated that the dietary Mg intake negatively correlated with osteoporosis, especially in participants aged 55 years or older. In addition, the non-linear relationship characterized by SCF and weighted GAM showed that the dietary Mg intake presented an L-shaped association with osteoporosis among females aged 55 years or older. Moreover, the weighted logistic regression model demonstrated that compared with MDS 0, the OR between MDS ≥3 and osteoporosis was 2.987 (95% CI 1.904, 4.686) in the male-middle intake group. Moreover, compared with MDS 0, the ORs between MDS ≥3 and osteoporosis was 5.666 (95% CI 3.188, 10.069) in the female-low intake group and 1.691 (95% CI 1.394, 2.051) in the female-middle intake group.
Conclusion
The present study indicated that in people with a daily intake of Mg level below the recommended daily intake (RDI), the dietary Mg intake and Mg bioavailability represented by MDS have a negative correlation with osteoporosis. According to the results, the combination of MDS and dietary Mg intake may be more comprehensive and rigorous in screening the population with osteoporosis. Therefore, early monitoring and interventions for osteoporosis may be necessary for those with insufficient dietary Mg intake or high MDS scores.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).
Confianza de la comunidad
Cargando…
¿Cuánto confías en los hallazgos de este estudio?
Comentarios
¿Algo está mal aquí?
Señala este estudio si su información, etiquetas o financiación parecen incorrectas. Un editor revisa cada señalamiento.
Información educativa sobre investigación publicada. No es consejo médico ni una recomendación para empezar o dejar nada.