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Effects of Blueberry Consumption on Cardiovascular Health in Healthy Adults: A Cross-Over Randomised Controlled Trial

Wang Y, Gallegos JL, Haskell-Ramsay C, Lodge JK

Nutrients · 22 citas

Cómo se estudió

Diseño
Ensayo controlado aleatorizado (indexado por PubMed)
Estudiado en
Personas
Resultado principal
Marcadores de salud y funcionamiento
Consumo medido con
No se indica

Quién lo pagó

Financiación
Financiación independiente

Según la declaración de financiación del texto completo.

Publicación

Publicado
2022-06-21 · Nutrients · vol. 14 · número 13 · pág. 2562
Editorial
Multidisciplinary Digital Publishing Institute
Citado
36 citas · más que el 90% de estudios similares · 2.6× el promedio de su campo
Impacto
Entre el 10 % más citado de su campo
Referencias
53 trabajos
Acceso
Acceso abierto (revista) · CC-BY
Áreas de investigación
Phytochemicals and Antioxidant Activities · Cardiovascular Health and Disease Prevention · Pomegranate: compositions and health benefits
Palabras clave
blueberry, cardiovascular health, polyphenols, endothelial dysfunction, hypertension, blood pressure, pulse wave velocity, plasma nitrite, serum cholesterol, triglycerides, young adults, dietary supplementation
MeSH
humans, nitrogen dioxide, glucose, powders, blood pressure, adult, cholesterol, ldl, cholesterol, hdl, young adult, blueberry plants

4 autores

  • Yueyue Wang🇬🇧Northumbria University
  • José Lara🇬🇧Northumbria University
  • Crystal F. Haskell‐Ramsay🇬🇧Northumbria University
  • John K. Lodge🇬🇧 · autor de correspondenciaLondon Metropolitan University; Northumbria University

Resumen

El texto original del estudio, en el idioma en que se publicó.

Blueberries are rich in polyphenols, and their effect on cardiovascular health, including risk factors for endothelial dysfunction and hypertension, has been investigated in interventional studies. However, the difference between blueberry treatments in varied forms for their cardiovascular-protective effect remains poorly understood. The current study assessed the effects of whole blueberry and freeze-dried blueberry powder compared to a control on cardiovascular health in young adults. A cross-over randomised controlled trial (RCT) was implemented with 1 week of treatment for three treatment groups, each followed by 1 week of wash out period. Systolic (SBP) and diastolic blood pressure (DBP), pulse wave velocity (PWV), plasma cholesterol (low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), and total cholesterol) and triglyceride levels (TAG), and glucose and nitrite (NO2-) concentrations were compared following fresh blueberry, freeze-dried blueberry powder, and control treatments. Thirty-seven participants with a mean age of 25.86 ± 6.81 completed the study. No significant difference was observed among fresh blueberry, blueberry powder, and the control arm. Plasma NO2- levels were improved by 68.66% and 4.34% separately following whole blueberry and blueberry powder supplementations compared to the baseline, whereas the control supplementation reported a decrease (-9.10%), although it was not statistically significant. There were no other effects shown for SBP, DBP, total cholesterol, HDL-C, LDL-C, TAG, or glucose. No difference was shown between whole blueberry and freeze-dried blueberry powder consumption for improving cardiovascular health.

Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).

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