Dietary recommendations for fasting days in an alternate-day intermittent fasting pattern: A randomized controlled trial
Xu S, Jiang Y, Zhang Y, Xu W, Zhang H, Yan Q, Gao L, Shang L
Nutrition (Burbank, Los Angeles County, Calif.) · 4 citas
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- China Postdoctoral Science Foundation
- Subvenciones
- China Postdoctoral Science Foundation (2018M643837); China Postdoctoral Science Foundation (2019 T120986)
Según 1 financiador declarado.
Publicación
- Publicado
- 2022-05-17 · Nutrition · vol. 102 · pág. 111735
- Editorial
- Elsevier BV
- Citado
- 8 citas · más que el 68% de estudios similares · 0.8× el promedio de su campo
- Referencias
- 21 trabajos
- Acceso
- De pago
- Áreas de investigación
- Dietary Effects on Health · Diet and metabolism studies · Nutritional Studies and Diet
- Palabras clave
- alternate-day fasting, intermittent fasting, weight loss, high-protein diet, hunger, lipid profile, triglycerides, low-density lipoprotein, Chinese adults, dietary recommendations
- MeSH
- humans, obesity, weight loss, body mass index, caloric restriction, fasting, adult
8 autores
- Shaoyong Xu🇨🇳Hubei University of Arts and Science; Xiangyang Central Hospital; Air Force Medical University
- Yuxin Jiang🇨🇳Yan'an University
- Yuhai Zhang🇨🇳Air Force Medical University
- Wenlei Xu🇨🇳Hubei University of Arts and Science; Xiangyang Central Hospital
- Hao Zhang🇨🇳Air Force Medical University
- Qiongjie Yan🇨🇳Hubei University of Arts and Science; Xiangyang Central Hospital
- Ling Gao🇨🇳Hubei University of Arts and Science; Xiangyang Central Hospital
- Lei Shang🇨🇳 · autor de correspondenciaAir Force Medical University
Resumen
El texto original del estudio, en el idioma en que se publicó.
Objectives
The aims of this study were to explore the safety and effectiveness of alternate-day fasting in Chinese people and to compare weight loss outcomes and safety when consuming a high-protein (HP) versus a normal protein (NP) diet versus a nutritional meal replacement (MR) on fasting days.
Methods
This was a randomized, open, parallel-controlled, interventional, exploratory trial, that included a 3-d run-in period and a 28-d intervention period. Adult participants without restriction of body mass index (N = 60) were randomly assigned to three alternative-day fasting (ADF) intervention groups: group HP, group NP, and group MR. The primary outcome was weight change from baseline at 28 d.
Results
Overall participants lost an average of 2.53 kg. Mean triacylglycerols, total cholesterol, and low-density lipoprotein were significantly reduced by 0.10, 0.15, and 0.11 mmol/L, respectively. The mean hunger scale on day 1 of fasting was 18.73 at breakfast and 45.25 at dinner. The mean hunger scale on the last day of fasting decreased significantly, to 10.89 at breakfast and 18.93 at dinner. Weight loss of groups HP, NP, and MR were 2.16, 2.63, and 2.94 kg, respectively; groups did not differ significantly (P = 0.841). The most common adverse events were dizziness, heart palpitations, and fatigue.
Conclusions
ADF is an effective, short-term weight loss strategy that was tolerated by most Chinese participants. We suggest that dietary patterns during fasting days is less important, and that calorie restriction during those days should be the focus.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
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