Financiado en parte por Malaysian Palm Oil Board
Diets enriched with palm olein, cocoa butter, and extra virgin olive oil exhibited similar lipid response: a randomized controlled study in young healthy adults
Loganathan R, Nagapan G, Teng KT, Voon PT, Yap SY, Ng YT, Ng TKW, Choo YM, Ong ASH, Ong SH, Selvaduray KR
Nutrition research (New York, N.Y.) · 10 citas
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Alimentación controladaFinanciado por la industriaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
- Consumo medido con
- Comida provista por los investigadores
Quién lo pagó
- Financiación
- Financiado por la industria
- Grupo de la industria
- Malaysian Palm Oil Board
- Subvenciones
- Malaysian Palm Oil Board (PD20515)
Según 1 financiador declarado.
Publicación
- Publicado
- 2022-07-06 · Nutr Res · vol. 105 · págs. 113–125
- Editorial
- Elsevier BV
- Citado
- 16 citas · más que el 83% de estudios similares · 1.8× el promedio de su campo
- Referencias
- 32 trabajos
- Acceso
- De pago
- Áreas de investigación
- Fatty Acid Research and Health · Edible Oils Quality and Analysis · Nuts composition and effects
- Palabras clave
- palm olein, cocoa butter, extra virgin olive oil, sn-2 palmitate, oleic acid, triglyceride structure, dietary fat, serum cholesterol, HDL cholesterol, LDL cholesterol, apolipoprotein B, apolipoprotein A-I, lipoprotein(a), triglycerides, bakery products, healthy young adults
- MeSH
- humans, dietary fats, oleic acid, triglycerides, plant oils, diet, adult, cholesterol, ldl, cholesterol, hdl, olive oil, palm oil
11 autores
- Radhika Loganathan🇲🇾Malaysian Palm Oil Board
- Gowri Nagapan🇲🇾Malaysian Palm Oil Board
- Kim‐Tiu Teng🇲🇾Malaysian Palm Oil Board
- Phooi Tee Voon🇲🇾Malaysian Palm Oil Board
- Sia-Yen Yap🇲🇾Malaysian Palm Oil Board
- Yen Teng Ng🇲🇾Malaysian Palm Oil Board
- Tony Kock Wai Ng🇲🇾Universiti Tunku Abdul Rahman
- Yuen May Choo🇲🇾Malaysian Oil Scientists and Technologists Association
- A. S. H. Ong🇲🇾Malaysian Oil Scientists and Technologists Association
- S. H. Ong🇲🇾UCSI University
- Kanga Rani Selvaduray🇲🇾 · autor de correspondenciaMalaysian Palm Oil Board
Resumen
El texto original del estudio, en el idioma en que se publicó.
Vegetable oils having unsaturated fatty acids in the sn-2 position of triglyceride (TG) backbone might not raise serum cholesterol levels. We investigated the chronic effects of diets enriched with palm olein (IV64) (PO), cocoa butter (CB), or extra virgin olive oil (EVOO) with oleic acid primarily at the sn-2 position (66%, 75%, 87% sn-2 oleic acid, respectively) of the TG molecule in 40 healthy volunteers participated in this randomized, controlled, single-blinded, crossover trial. Following a 2-week run-in period, the subjects were given standardization meals (breakfast, lunch, and dinner) cooked with palm olein (IV72). Subjects were randomized to 1 of the 3 intervention groups; receiving baked products (brownies for breakfast and cookies for teatime) prepared with respective test fats accompanied with standardized low-fat meals for breakfast, lunch, and dinner prepared with palm olein (IV72) for all groups for 4 weeks in a crossover manner with 2-week washout period (given standardization meals). Anthropometric measurements, blood samples, and dietary intakes were measured before run-in and pre- and post-intervention. No significant difference was observed on the primary outcome of the study total: high-density lipoprotein cholesterol. All 3 test fats were found to exhibit similar lipid responses (total cholesterol, TG, lipoprotein (a), apolipoprotein-A1, apolipoprotein-B/A-1). Statistical difference was found on low-density lipoprotein cholesterol (CB>EVOO by 0.3 mmol/L, P = .003), high-density lipoprotein cholesterol (PO>CB by 0.04 mmol/L, P = .02) and apolipoprotein-B (EVOO<PO and CB by 0.03 mmol/L, P = .01 and 0.04 mmol, P = .001 respectively). Diets with PO, CB, and EVOO have almost similar lipid profiles and homeostatic model assessment measures.
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