The relationship between habitual water intake and dry eye disease
Nguyen L, Magno MS, Utheim TP, Jansonius NM, Hammond CJ, Vehof J
Acta ophthalmologica · 8 citas
Cómo se estudió
- Diseño
- Estudio transversal (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
- Universidad u hospital
- Rijksuniversiteit Groningen
- Universidad u hospital
- Universitair Medisch Centrum Groningen
Según 2 financiadores declarados y la declaración de financiación del texto completo.
Publicación
- Publicado
- 2022-08-08 · Acta Ophthalmol · vol. 101 · número 1 · págs. 65–73
- Editorial
- Wiley
- Citado
- 13 citas · más que el 85% de estudios similares · 1.9× el promedio de su campo
- Referencias
- 45 trabajos
- Acceso
- Acceso abierto (revista híbrida) · CC-BY-NC-ND
- Áreas de investigación
- Ocular Surface and Contact Lens · Dermatology and Skin Diseases · Allergic Rhinitis and Sensitization
- Palabras clave
- Medicine, Body mass index, Logistic regression, Population, Cohort, Urine, Disease, Water intake, Cohort study, Demography, Internal medicine, Environmental health
- MeSH
- humans, dry eye syndromes, water, prevalence, risk factors, cross-sectional studies, middle aged, female, surveys and questionnaires
6 autores
- Long H. Nguyen🇳🇴Oslo University Hospital
- Morten Schjerven Magnø🇳🇴🇳🇱Oslo University Hospital; University Medical Center Groningen; University of Groningen; Sørlandet Hospital Arendal
- Tor Paaske Utheim🇳🇴Oslo University Hospital; Sørlandet Hospital Arendal
- Nomdo M. Jansonius🇳🇱University Medical Center Groningen; University of Groningen
- Christopher Joseph Hammond🇬🇧St Thomas' Hospital; King's College London
- Jelle Vehof🇳🇱🇳🇴 · autor de correspondenciaUniversity Medical Center Groningen; University of Groningen; Sykehuset i Vestfold; Rotterdam Eye Hospital
Resumen
El texto original del estudio, en el idioma en que se publicó.
Purpose
The purpose of this study is to test the hypothesis that greater habitual water intake is associated with lower risk of dry eye disease (DED).
Methods
We included 51 551 participants from the population-based Lifelines cohort (mean age = 51.2 years) in this cross-sectional association study. DED was assessed using the Women's Health Study (WHS) dry eye questionnaire. Water intake was calculated from food frequency questionnaires. Logistic regressions were used to analyse the relationship between DED and water intake or 24-h urine volume, corrected for age, sex, body mass index, physical activity, smoking status, education, income, 48 comorbidities, and 15 medication groups. The main outcome measure was WHS-defined DED. Highly symptomatic dry eye and clinical diagnosis of DED were secondary outcomes.
Results
In total, 9.1% of the population had WHS-defined DED. Higher water intake was associated with increased prevalence of WHS-defined DED (OR: 1.011 per 100 ml/day, 95% CI: 1.004-1.017, p = 0.003). After excluding those with a clinical diagnosis, greater water intake was still tied to increased risk of having DED symptoms (OR: 1.010 per 100 ml/day, 95% CI: 1.006-1.015, p < 0.001). Higher 24-h urine volumes were also associated with higher risk of WHS-defined DED (OR: 1.010 per 100 ml/day, 95% CI: 1.005-1.015, p < 0.001).
Conclusions
In this large, population-based study, higher water intake was not tied to reduced risk of DED. Rather, it was associated with a modest increased risk of DED. Interventional studies are needed to fully understand the effect of water intake on DED, but this study found no evidence that greater water intake is beneficial for DED.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY-NC-ND).
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