Dietary consumption of cruciferous vegetables and bladder cancer risk: A systematic review and meta-analysis
Yu P, Yu L, Lu Y
Frontiers in nutrition · 6 citas
Cómo se estudió
- Diseño
- Revisión sistemática (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Eventos clínicos como enfermedad o muerte
- Consumo medido con
- No se indica
Quién lo pagó
- Financiación
- Financiación independiente
Según la declaración de financiación del texto completo.
Publicación
- Publicado
- 2022-08-18 · Front Nutr · vol. 9 · pág. 944451
- Editorial
- Frontiers Media
- Citado
- 8 citas · más que el 32% de estudios similares · 0.2× el promedio de su campo
- Referencias
- 41 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY
- Áreas de investigación
- Genomics, phytochemicals, and oxidative stress · Antioxidant Activity and Oxidative Stress · Sulfur Compounds in Biology
- Palabras clave
- Cruciferous vegetables, Medicine, Meta-analysis, Bladder cancer, Publication bias, Cohort study, Relative risk, Confidence interval, Funnel plot, Cancer, Lower risk, Internal medicine, Environmental health
3 autores
- Pengkui Yu🇨🇳 · autor de correspondenciaSheng Jing Hospital; Zhejiang University
- Lin Juan Yu🇨🇳Sheng Jing Hospital; Zhejiang University
- Yi Lu🇨🇳 · autor de correspondenciaSheng Jing Hospital; Zhejiang University
Resumen
El texto original del estudio, en el idioma en que se publicó.
Objective
Previous studies on the association of cruciferous vegetables intake with bladder cancer risk have reported inconsistent results. We performed the present meta-analysis to summarize evidence on this association and to quantify the potential dose-response relation based on all available cohort studies.
Methods
A comprehensive literature search of relevant articles up to March 2022 was performed in PubMed and EMBASE. The summary risk estimates with 95% confidence intervals for the highest vs. the lowest intake of cruciferous vegetables were calculated. Dose-response meta-analysis was also performed for studies reporting categorical risk estimates for at least three quantitative levels of cruciferous vegetables intake.
Results
We found that the highest cruciferous vegetables intake was not significantly associated with a lower risk of bladder cancer, compared with the lowest cruciferous vegetables intake category (RR = 0.92, 95% CI 0.80-1.06). Linear dose-response meta-analysis indicated that the pooled RRs for 10 g/day or 1 servings/week increment of cruciferous vegetables intake was not significantly associated with a reduced risk of bladder cancer (P = 0.106 and P = 0.147, respectively). There was no evidence of significant publication bias either with Begg's test (P = 0.386) or Egger's test (P = 0.253).
Conclusion
The results of this study did not support the hypothesis that dietary cruciferous vegetables intake was associated with a lower risk of bladder cancer. Further large prospective cohort studies are warranted to confirm our preliminary findings.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).
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