The effect of dietary nitrate on macro- and microvascular function: A systematic review
Volino-Souza M, Oliveira GV, Pinheiro VDS, Conte-Junior CA, Alvares TDS
Critical reviews in food science and nutrition · 11 citas
Cómo se estudió
- Diseño
- Revisión sistemática (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
- Consumo medido con
- No se indica
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- by CAPES (Brazil) and FAPERJ
- Gobierno
- FAPERJ Young Scientist
Según 2 financiadores declarados.
Publicación
- Publicado
- 2022-09-05 · Crit Rev Food Sci Nutr · vol. 64 · número 5 · págs. 1225–1236
- Editorial
- Taylor & Francis
- Citado
- 15 citas · más que el 46% de estudios similares · 0.4× el promedio de su campo
- Referencias
- 68 trabajos
- Acceso
- De pago
- Áreas de investigación
- Nitric Oxide and Endothelin Effects · Cardiovascular Health and Disease Prevention · Cerebrovascular and Carotid Artery Diseases
- Palabras clave
- Nitrate, Ingestion, Bioavailability, Nitric oxide, Dietary Nitrate, Function (biology), Chemistry, Physiology, Internal medicine, Medicine, Nitrite, Pharmacology, Biochemistry, Biology
- MeSH
- humans, nitrates, nitric oxide, diet, dietary supplements, microvessels
5 autores
- Mônica Volino‐Souza🇧🇷Universidade Federal do Rio de Janeiro
- Gustavo Vieira de Oliveira🇧🇷Universidade Federal do Rio de Janeiro; Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro
- Vivian dos Santos Pinheiro🇧🇷Universidade Federal do Rio de Janeiro
- Carlos Adam Conte‐Júnior🇧🇷Universidade Federal do Rio de Janeiro; Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro
- Thiago Silveira Álvares🇧🇷 · autor de correspondenciaUniversidade Federal do Rio de Janeiro
Resumen
El texto original del estudio, en el idioma en que se publicó.
Previous studies have investigated the impact of dietary nitrate on vascular function due to the association between dietary nitrate ingestion and improvement in nitric oxide (NO) bioavailability. Considering that NO can present different effects through vascular beds (macro- vs. microvasculature) due to the specific characteristic (function and morphology) that each vessel exhibits, it is crucial to investigate the effect of dietary nitrate ingestion on the macro- and microvascular function to understand the effect of nitrate on vascular function. For this reason, this review aimed to evaluate the impact of dietary nitrate on macro- and microvascular function in humans. A total of 29 studies were included in the systematic review, of which 19 studies evaluated the effect of nitrate supplementation on macrovascular function, eight studies evaluated the effect on microvascular function, and two studies evaluated the impact on both macro- and microvascular function. The literature suggests that dietary nitrate ingestion seems to improve the vascular function in macrovasculature, whereas microvascular function appears to be modest. Future studies investigating the effect of nitrate ingestion on vascular function should focus on measuring macro- and microvascular function whenever possible so that the impact of nitrate-rich foods on vascular segments could be better understood.
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