Immediate Effect in the Retina and Choroid after 650 nm Low-Level Red Light Therapy in Children
Yang W, Lin F, Li M, Wei R, Zhou J, Zhou X
Ophthalmic research · 26 citas
Cómo se estudió
- Diseño
- Estudio de cohortes (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- National Natural Science Foundation of China
- Gobierno
- Shanghai Rising-Star Program
- Subvenciones
- National Natural Science Foundation of China (81770955); National Natural Science Foundation of China (SHDC12018103); National Natural Science Foundation of China (20410710100); Shanghai Rising-Star Program (21QA1401500)
Según 2 financiadores declarados.
Publicación
- Publicado
- 2022-10-31 · Ophthalmic Res · vol. 66 · número 1 · págs. 312–318
- Editorial
- Karger Publishers
- Citado
- 35 citas · más que el 93% de estudios similares · 3.4× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 33 trabajos
- Acceso
- Acceso abierto (publicación gratuita) · CC-BY-NC
- Áreas de investigación
- Laser Applications in Dentistry and Medicine · Ophthalmology and Visual Impairment Studies · Retinal Diseases and Treatments
- Palabras clave
- Ophthalmology, Choroid, Retinal, Medicine, Retina, Optical coherence tomography, Significant difference, Fluorescein angiography, Mean difference, Confidence interval, Optics, Internal medicine, Physics
- MeSH
- retina, choroid, humans, tomography, optical coherence, prospective studies, child, china, red light
6 autores
- Weiming Yang🇨🇳Chinese Academy of Medical Sciences & Peking Union Medical College; Fudan University; Shanghai Eye Disease Prevention & Treatment Center; Eye & ENT Hospital of Fudan University; Shanghai Clinical Research Center; Children's Hospital of Fudan University
- Feng Lin🇨🇳Chinese Academy of Medical Sciences & Peking Union Medical College; Fudan University; Shanghai Eye Disease Prevention & Treatment Center; Eye & ENT Hospital of Fudan University; Shanghai Clinical Research Center
- Meiyan Li🇨🇳Chinese Academy of Medical Sciences & Peking Union Medical College; Fudan University; Shanghai Eye Disease Prevention & Treatment Center; Eye & ENT Hospital of Fudan University; Shanghai Clinical Research Center
- Ruoyan Wei🇨🇳Chinese Academy of Medical Sciences & Peking Union Medical College; Fudan University; Shanghai Eye Disease Prevention & Treatment Center; Eye & ENT Hospital of Fudan University; Shanghai Clinical Research Center
- Jiaqi Zhou🇨🇳Chinese Academy of Medical Sciences & Peking Union Medical College; Fudan University; Shanghai Eye Disease Prevention & Treatment Center; Eye & ENT Hospital of Fudan University; Shanghai Clinical Research Center
- Xingtao Zhou🇨🇳Chinese Academy of Medical Sciences & Peking Union Medical College; Fudan University; Shanghai Eye Disease Prevention & Treatment Center; Eye & ENT Hospital of Fudan University; Shanghai Clinical Research Center
Resumen
El texto original del estudio, en el idioma en que se publicó.
Introduction
The objective of this study was to investigate the changes in the retina and choroid of children after 650 nm low-level red light therapy (LLRLT).
Methods
In this prospective study, 25 subjects in the Shanghai Eye and ENT Hospital of Fudan University were included from August 2021 to September 2021. One eye was randomly selected to receive LLRLT for 3 min. Swept-source optical coherence tomography (OCT) and OCT angiography were used to measure retinal fovea perfusion density (RFPD), retinal fovea thickness (RFT), choroidal fovea blood flow (CFBF), and choroidal fovea thickness (CFT) before LLRLT, 5 min and 1 h after LLRLT. Baseline characteristics between LLRLT and non-LLRLT eyes were compared. Changes in the retinal and choroidal parameters were analyzed by ANCOVA models. SAS software was used for data analysis. The difference was considered statistically significant if p < 0.05.
Results
There was no difference in baseline characteristics between LLRLT eyes and non-LLRLT eyes. The RFPD in LLRLT eyes significantly increased 5 min after LLRLT, and the increment was 1.70 ± 0.83% (p = 0.0389). The RFPD significantly decreased from 5 min to 1 h after LLRLT with a mean of -2.62 ± 0.86% decrement (p = 0.0031). The RFPD levels returned to baseline at 1 h after LLRLT (p = 0.8646). However, compared with insignificant RFPD changes in non-LLRLT eyes, there was no significant difference in RFPD changes at any sampling point. No significant changes in RFT, CFBF, and CFT were found in LLRLT eyes at each sampling point.
Conclusion
Although 3 min of LLRLT has no effect on the choroid, it may cause a short-term transient increase in RFPD. It will provide theoretical support for the role of LLRLT in myopia control.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY-NC).
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