The effect of almond intake on cardiometabolic risk factors, inflammatory markers, and liver enzymes: A systematic review and meta-analysis
Morvaridzadeh M, Qorbani M, Shokati Eshkiki Z, Estêvão MD, Mohammadi Ganjaroudi N, Toupchian O, Abdollahi S, Pizarro AB, Abu-Zaid A, Zadro JR, Heshmati J, Ziaei S
Phytotherapy research : PTR · 11 citas
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Publicación
- Publicado
- 2022-11-04 · Phytother Res · vol. 36 · número 12 · págs. 4325–4344
- Editorial
- Wiley
- Citado
- 12 citas · más que el 55% de estudios similares · 0.7× el promedio de su campo
- Referencias
- 78 trabajos
- Acceso
- Lectura gratuita
- Áreas de investigación
- Nuts composition and effects · Nutritional Studies and Diet · Fatty Acid Research and Health
- Palabras clave
- cardiometabolic risk factors, blood pressure, lipid profile, cholesterol, triglycerides, LDL cholesterol, HDL cholesterol, insulin resistance, glycemic control, inflammatory markers, liver enzymes, C-reactive protein, interleukin-6, TNF-α, homocysteine, antihypertensive effect, hypolipidemic effect
- MeSH
- liver, humans, transferases, prunus dulcis, cardiometabolic risk factors
12 autores
- Mojgan Morvaridzadeh🇮🇷Kermanshah University of Medical Sciences
- Mostafa Qorbani🇮🇷Alborz University of Medical Sciences; Endocrinology and Metabolism Population Sciences Institute; Tehran University of Medical Sciences
- Zahra Shokati Eshkiki🇮🇷Ahvaz Jundishapur University of Medical Sciences
- M. Dulce Estêvão🇵🇹University of Algarve
- Negar Mohammadi Ganjaroudi🇮🇷Shahid Beheshti University; Shahid Beheshti University of Medical Sciences
- Omid Toupchian🇮🇷North Khorasan University of Medical Sciences
- Shima Abdollahi🇮🇷North Khorasan University of Medical Sciences
- Ana Beatriz Pizarro🇨🇴Fundación Valle del Lili
- Ahmed Abu‐Zaid🇺🇸University of Tennessee Health Science Center
- Joshua Robert Zadro🇦🇺The University of Sydney
- Javad Heshmati🇮🇷 · autor de correspondenciaKermanshah University of Medical Sciences
- Somayeh Ziaei🇮🇷 · autor de correspondenciaKermanshah University of Medical Sciences; Emam Reza Hospital
Resumen
El texto original del estudio, en el idioma en que se publicó.
Almond intake may be correlated with improvements in several cardiometabolic parameters, but its effects are controversial in the published literature, and it needs to be comprehensively summarized. We conducted a systematic search in several international electronic databases, including MEDLINE, EMBASE, Scopus, Web of Science, Cochrane Central Register of Controlled Trials, and ClinicalTrials.gov until April 2021 to identify randomized controlled trials that examined the effects of almond consumption on cardiometabolic risk factors, inflammatory markers, and liver enzymes. Data were pooled using the random-effects model method and presented as standardized mean differences (SMDs) with 95% confidence intervals (CIs). Twenty-six eligible trials were analyzed (n = 1750 participants). Almond intake significantly decreased diastolic blood pressure, total cholesterol, triglyceride, low-density lipoprotein (LDL), non-high-density lipoprotein (HDL), and very LDL (p .05). The current body of evidence supports the ingestion of almonds for their beneficial lipid-lowering and antihypertensive effects. However, the effects of almonds on antiinflammatory markers, glycemic control, and hepatic enzymes should be further evaluated via performing more extensive randomized trials.
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