Beneficial effect of time-restricted eating on blood pressure: a systematic meta-analysis and meta-regression analysis
Wang W, Wei R, Pan Q, Guo L
Nutrition & metabolism · 31 citas
Cómo se estudió
- Diseño
- Metaanálisis (clasificado por nuestro filtro de IA)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- National Natural Science Foundation of China
- Subvenciones
- National Natural Science Foundation of China (82170848)
Según 1 financiador declarado y la declaración de financiación del texto completo.
Publicación
- Publicado
- 2022-11-08 · Nutr Metab (Lond) · vol. 19 · número 1 · pág. 77
- Editorial
- BioMed Central
- Citado
- 39 citas · más que el 94% de estudios similares · 3.3× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 46 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY
- Áreas de investigación
- Dietary Effects on Health · Enhanced Recovery After Surgery · Circadian rhythm and melatonin
- Palabras clave
- Blood pressure, Medicine, Meta-analysis, Cochrane Library, Internal medicine, Meta-regression, Clinical nutrition, Heart rate, Cardiology, Surgery
4 autores
- Weihao Wang🇨🇳Chinese Academy of Medical Sciences & Peking Union Medical College
- Ran Wei🇨🇳Chinese Academy of Medical Sciences & Peking Union Medical College; Peking University
- Qi Pan🇨🇳 · autor de correspondenciaChinese Academy of Medical Sciences & Peking Union Medical College
- Lixin Guo🇨🇳 · autor de correspondenciaChinese Academy of Medical Sciences & Peking Union Medical College; Peking University; Peking University People's Hospital
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background
As a cardiometabolic disease, hypertension has shown an obvious upward trend, becoming a global epidemic chronic disease. Lifestyle intervention is a fundamental method for lowering blood pressure. This systematic review and meta-analysis aimed to evaluate the effects of time-restricted eating (TRE) on blood pressure.
Methods
Studies were retrieved from the PubMed, Embase, Cochrane Library, and Web of Science databases to evaluate the effects of TRE on blood pressure. The time frame of search was from the start of database construction until July 14, 2022.There were no language restrictions. Meta-analysis and meta-regression were performed using Stata version 16. The weighted mean difference with 95% CI was used to assess the effect of TRE on blood pressure, heart rate, weight, blood glucose, total cholesterol, HDL-C, LDL-C, and triglycerides. The main ending of this article were blood pressure and heart rate, while the secondary ending were weight, blood glucose, total cholesterol, HDL-C, LDL-C, and triglycerides.
Results
Ten randomized controlled trials involving 694 patients were identified. TRE significantly reduced systolic blood pressure (SBP) (mean difference = -4.15; 95% CI: -6.73, -2.30; P < 0.0001), but had no significant effect on diastolic blood pressure (DBP) (mean difference = -2.06; 95% CI: -4.16, 0.02; P = 0.053) and no beneficial effect on heart rate (mean difference = 0.36; 95% CI: -2.83, 3.54; P = 0.0825). TRE promoted weight loss (mean difference = -1.63; 95% CI: -2.61, -0.64; P = 0.001) and decreased blood glucose levels (mean difference = -2.80; 95% CI: -4.64, -0.96; P = 0.003), but had no significant effect on total cholesterol (mean difference = 0.03, 95% CI: -10.01, 10.08; P = 0.995), HDL-C (mean difference = 0.85, 95% CI: -1.80, 3.49; P = 0.531), LDL-C (mean difference = -0.86, 95% CI: -6.47, 4.76; P = 0.764), or triglycerides (mean difference = -3.524, 95% CI: -9.49, 2.45; P = 0.248). In a separate meta-regression analysis, the degree of SBP change was related to weight loss (P = 0.044) but not to glucose improvement (P = 0.867).
Conclusions
The present meta-analysis suggests that TRE significantly reduced SBP, while no effect of reducing DBP was seen. The observed lower blood pressure may be attributed to significant weight loss. The effects of TRE on heart rate and blood lipid levels were not apparent.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).
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