Can transcranial photobiomodulation improve cognitive function? A systematic review of human studies
Lee TL, Ding Z, Chan AS
Ageing research reviews · 38 citas
Cómo se estudió
- Diseño
- Revisión sistemática (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
- Universidad u hospital
- Chinese University of Hong Kong
Según 1 financiador declarado.
Publicación
- Publicado
- 2022-11-09 · Ageing Res Rev · vol. 83 · pág. 101786
- Editorial
- Elsevier BV
- Citado
- 58 citas · más que el 93% de estudios similares · 2.5× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 87 trabajos
- Acceso
- De pago
- Áreas de investigación
- Laser Applications in Dentistry and Medicine · Optical Imaging and Spectroscopy Techniques · Biofield Effects and Biophysics
- Palabras clave
- transcranial photobiomodulation, cognitive function, learning and memory, attention, executive function, mild cognitive impairment, dementia, traumatic brain injury, stroke, near-infrared light, red light therapy, light wavelength
- MeSH
- humans, cognition, cognition disorders, executive function, cognitive dysfunction, brain injuries, traumatic
3 autores
- Tsz‐lok Lee🇭🇰Chinese University of Hong Kong
- Zihan Ding🇭🇰Chinese University of Hong Kong
- Agnes Sui-Yin Chan🇭🇰 · autor de correspondenciaChinese University of Hong Kong
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background
Transcranial photobiomodulation (tPBM) has been studied for over a decade as a possible cognitive intervention.
Objective
To evaluate the effect of tPBM for enhancing human cognitive function in healthy adults and remediating impaired cognitive function in adults with cognitive disorders.
Methods
A systematic literature search from three electronic databases (PubMed, Scopus, Web of Science) was conducted from 1987 to May 2022. The cognitive function being evaluated included learning and memory, attention, executive function, language, and global cognitive function.
Results
Of the 35 studies identified, 29 (82.9 %) studies reported positive improvement in cognitive functions after tPBM. All nine studies on participants with subjective memory complaints, mild cognitive impairment, and dementia, showed positive outcomes. Seven (87.5 %) studies on traumatic brain injury (TBI) patients also showed positive results. A series of clinical trials on stroke patients showed positive trends on improved neurological deficit at first, but was prematurely terminated later at phase III due to the lack of statistical significance. One of the most common protocols for clinical populations employed devices delivering near-infrared light (810 nm), the irradiance of 20-25 mW/cm2, and fluence of 1-10 J/cm2. While this was common, the reviewed protocols also included other wavelengths of light ranging from visible, red (630-635 nm) to invisible near-infrared maximum wavelengths of 1060-1068 nm.
Conclusions
tPBM seems to improve cognitive function. However, only half of the reviewed clinical trials were randomized control trials, further investigation is warranted.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
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